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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG009737

Entrez Gene ID

51343

Official Gene Symbol

FZR1

Synonyms

CDC20C|CDH1|FZR|FZR2|HCDH|HCDH1|KIAA1242

Gene name

fizzy/cell division cycle 20 related 1 (Drosophila)

Gene Type

protein-coding

Chromosome

19

Genomics Location

19p13.3

Known cancer genes

Yes

Protein products

Fizzy-related protein homolog

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:24824
MIM:603619
Ensembl:ENSG00000105325
HPRD:04687
RefSeq Genomic nucleotide accession:AC_000062
RefSeq Genomic nucleotide gi:89161197

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0000084

S phase of mitotic cell cycle

GO:0000278

mitotic cell cycle

GO:0005515

protein binding

GO:0005634

nucleus

GO:0005654

nucleoplasm

GO:0005680

anaphase-promoting complex

GO:0005737

cytoplasm

GO:0005829

cytosol

GO:0006281

DNA repair

GO:0007067

mitosis

GO:0031145

anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process

GO:0031572

G2/M transition DNA damage checkpoint

GO:0040020

regulation of meiosis

GO:0045732

positive regulation of protein catabolic process

GO:0051301

cell division

GO:0051436

negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle

GO:0051437

positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle

GO:0051439

regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle

GO:0051488

activation of anaphase-promoting complex activity

GO:0070306

lens fiber cell differentiation