Choose one of the five choices you want to search:

Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG009749

Entrez Gene ID

51366

Official Gene Symbol

UBR5

Synonyms

DD5|EDD|EDD1|FLJ11310|HYD|KIAA0896|MGC57263

Gene name

ubiquitin protein ligase E3 component n-recognin 5

Gene Type

protein-coding

Chromosome

8

Genomics Location

8q22

Known cancer genes

Yes

Protein products

E3 ubiquitin-protein ligase UBR5

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:16806
MIM:608413
Ensembl:ENSG00000104517
HPRD:06436
RefSeq Genomic nucleotide accession:AC_000051
RefSeq Genomic nucleotide gi:89161214

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0000209

protein polyubiquitination

GO:0003723

RNA binding

GO:0004842

ubiquitin-protein ligase activity

GO:0005515

protein binding

GO:0005622

intracellular

GO:0005625

soluble fraction

GO:0005634

nucleus

GO:0006464

protein modification process

GO:0006511

ubiquitin-dependent protein catabolic process

GO:0006974

response to DNA damage stimulus

GO:0008270

zinc ion binding

GO:0008283

cell proliferation

GO:0016567

protein ubiquitination

GO:0016874

ligase activity

GO:0016881

acid-amino acid ligase activity

GO:0033160

positive regulation of protein import into nucleus, translocation

GO:0034450

ubiquitin-ubiquitin ligase activity

GO:0035413

positive regulation of catenin import into nucleus

GO:0042787

protein ubiquitination involved in ubiquitin-dependent protein catabolic process

GO:0046872

metal ion binding

GO:0050847

progesterone receptor signaling pathway

GO:0090263

positive regulation of canonical Wnt receptor signaling pathway