Gene basic information
LiverAtlas Gene ID |
HuLG009749 |
Entrez Gene ID |
|
Official Gene Symbol |
UBR5 |
Synonyms |
DD5|EDD|EDD1|FLJ11310|HYD|KIAA0896|MGC57263 |
Gene name |
ubiquitin protein ligase E3 component n-recognin 5 |
Gene Type |
protein-coding |
Chromosome |
8 |
Genomics Location |
8q22 |
Known cancer genes |
Yes |
Protein products |
|
Related liver disease name |
|
Database cross reference |
HGNC:16806
|
Liver relevance
HCC significant genes |
Yes/No |
Yes |
Evidence |
EHCO |
|
Quality score |
|
Ontology annotation
GO ID |
GO annotation |
GO:0000209 |
protein polyubiquitination |
GO:0003723 |
RNA binding |
GO:0004842 |
ubiquitin-protein ligase activity |
GO:0005515 |
protein binding |
GO:0005622 |
intracellular |
GO:0005625 |
soluble fraction |
GO:0005634 |
nucleus |
GO:0006464 |
protein modification process |
GO:0006511 |
ubiquitin-dependent protein catabolic process |
GO:0006974 |
response to DNA damage stimulus |
GO:0008270 |
zinc ion binding |
GO:0008283 |
cell proliferation |
GO:0016567 |
protein ubiquitination |
GO:0016874 |
ligase activity |
GO:0016881 |
acid-amino acid ligase activity |
GO:0033160 |
positive regulation of protein import into nucleus, translocation |
GO:0034450 |
ubiquitin-ubiquitin ligase activity |
GO:0035413 |
positive regulation of catenin import into nucleus |
GO:0042787 |
protein ubiquitination involved in ubiquitin-dependent protein catabolic process |
GO:0046872 |
metal ion binding |
GO:0050847 |
progesterone receptor signaling pathway |
GO:0090263 |
positive regulation of canonical Wnt receptor signaling pathway |