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Gene basic information

LiverAtlas Gene ID

HuLG009919

Entrez Gene ID

51684

Official Gene Symbol

SUFU

Synonyms

PRO1280|SUFUH|SUFUXL

Gene name

suppressor of fused homolog (Drosophila)

Gene Type

protein-coding

Chromosome

10

Genomics Location

10q24.32

Known cancer genes

Yes

Protein products

Suppressor of fused homolog (Drosophila)

Suppressor of fused homolog (Drosophila)

Suppressor of fused homolog (Drosophila)

Suppressor of fused homolog

Database cross reference

HGNC:16466
MIM:607035
Ensembl:ENSG00000107882
HPRD:06124
RefSeq Genomic nucleotide accession:AC_000053
RefSeq Genomic nucleotide gi:89161186

 

Ontology annotation

GO ID

GO annotation

GO:0000122

negative regulation of transcription from RNA polymerase II promoter

GO:0001501

skeletal system development

GO:0001843

neural tube closure

GO:0001947

heart looping

GO:0003714

transcription corepressor activity

GO:0004871

signal transducer activity

GO:0005515

protein binding

GO:0005634

nucleus

GO:0005730

nucleolus

GO:0005737

cytoplasm

GO:0005929

cilium

GO:0006355

regulation of transcription, DNA-dependent

GO:0006508

proteolysis

GO:0007165

signal transduction

GO:0007275

multicellular organismal development

GO:0007368

determination of left/right symmetry

GO:0008013

beta-catenin binding

GO:0008134

transcription factor binding

GO:0021513

spinal cord dorsal/ventral patterning

GO:0042802

identical protein binding

GO:0042994

cytoplasmic sequestering of transcription factor

GO:0043588

skin development

GO:0045879

negative regulation of smoothened signaling pathway