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Gene basic information

LiverAtlas Gene ID

HuLG010017

Entrez Gene ID

53905

Official Gene Symbol

DUOX1

Synonyms

LNOX1|MGC138840|MGC138841|NOXEF1|THOX1

Gene name

dual oxidase 1

Gene Type

protein-coding

Chromosome

15

Genomics Location

15q15.3

Known cancer genes

Yes

Protein products

Dual oxidase 1

Dual oxidase 1

Related liver disease name

Liver fibrosis and liver cirrhosis

Database cross reference

HGNC:3062
MIM:606758
Ensembl:ENSG00000137857
HPRD:08421
RefSeq Genomic nucleotide accession:AC_000058
RefSeq Genomic nucleotide gi:89161193

 

Ontology annotation

GO ID

GO annotation

GO:0004601

peroxidase activity

GO:0005509

calcium ion binding

GO:0005886

plasma membrane

GO:0006979

response to oxidative stress

GO:0009055

electron carrier activity

GO:0016021

integral to membrane

GO:0016174

NAD(P)H oxidase activity

GO:0016324

apical plasma membrane

GO:0016491

oxidoreductase activity

GO:0019221

cytokine-mediated signaling pathway

GO:0020037

heme binding

GO:0042335

cuticle development

GO:0042446

hormone biosynthetic process

GO:0042554

superoxide anion generation

GO:0042744

hydrogen peroxide catabolic process

GO:0050660

flavin adenine dinucleotide binding

GO:0050661

NADP binding

GO:0050665

hydrogen peroxide biosynthetic process

GO:0051591

response to cAMP

GO:0055114

oxidation-reduction process