Gene basic information
| LiverAtlas Gene ID |
HuLG010042 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
TLR9 |
|
Synonyms |
CD289 |
|
Gene name |
toll-like receptor 9 |
|
Gene Type |
protein-coding |
|
Chromosome |
3 |
|
Genomics Location |
3p21.3 |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Related liver disease name |
|
|
Database cross reference |
HGNC:15633
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0002237 |
response to molecule of bacterial origin |
|
GO:0004888 |
transmembrane receptor activity |
|
GO:0005149 |
interleukin-1 receptor binding |
|
GO:0005515 |
protein binding |
|
GO:0005576 |
extracellular region |
|
GO:0005737 |
cytoplasm |
|
GO:0005764 |
lysosome |
|
GO:0005768 |
endosome |
|
GO:0005783 |
endoplasmic reticulum |
|
GO:0005789 |
endoplasmic reticulum membrane |
|
GO:0005886 |
plasma membrane |
|
GO:0007165 |
signal transduction |
|
GO:0007252 |
I-kappaB phosphorylation |
|
GO:0008286 |
insulin receptor signaling pathway |
|
GO:0008543 |
fibroblast growth factor receptor signaling pathway |
|
GO:0010008 |
endosome membrane |
|
GO:0016021 |
integral to membrane |
|
GO:0016323 |
basolateral plasma membrane |
|
GO:0016324 |
apical plasma membrane |
|
GO:0030277 |
maintenance of gastrointestinal epithelium |
|
GO:0031410 |
cytoplasmic vesicle |
|
GO:0032009 |
early phagosome |
|
GO:0032088 |
negative regulation of NF-kappaB transcription factor activity |
|
GO:0032715 |
negative regulation of interleukin-6 production |
|
GO:0032717 |
negative regulation of interleukin-8 production |
|
GO:0032722 |
positive regulation of chemokine production |
|
GO:0032728 |
positive regulation of interferon-beta production |
|
GO:0032733 |
positive regulation of interleukin-10 production |
|
GO:0032735 |
positive regulation of interleukin-12 production |
|
GO:0032741 |
positive regulation of interleukin-18 production |
|
GO:0032755 |
positive regulation of interleukin-6 production |
|
GO:0032757 |
positive regulation of interleukin-8 production |
|
GO:0032760 |
positive regulation of tumor necrosis factor production |
|
GO:0034122 |
negative regulation of toll-like receptor signaling pathway |
|
GO:0034123 |
positive regulation of toll-like receptor signaling pathway |
|
GO:0035197 |
siRNA binding |
|
GO:0042346 |
positive regulation of NF-kappaB import into nucleus |
|
GO:0042742 |
defense response to bacterium |
|
GO:0043123 |
positive regulation of I-kappaB kinase/NF-kappaB cascade |
|
GO:0043507 |
positive regulation of JUN kinase activity |
|
GO:0045078 |
positive regulation of interferon-gamma biosynthetic process |
|
GO:0045087 |
innate immune response |
|
GO:0045356 |
positive regulation of interferon-alpha biosynthetic process |
|
GO:0045359 |
positive regulation of interferon-beta biosynthetic process |
|
GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
|
GO:0046330 |
positive regulation of JNK cascade |
|
GO:0050729 |
positive regulation of inflammatory response |
|
GO:0051092 |
positive regulation of NF-kappaB transcription factor activity |
|
GO:0051770 |
positive regulation of nitric-oxide synthase biosynthetic process |
