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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG010105

Entrez Gene ID

54476

Official Gene Symbol

RNF216

Synonyms

TRIAD3|U7I1|UBCE7IP1|ZIN

Gene name

ring finger protein 216

Gene Type

protein-coding

Chromosome

7

Genomics Location

7p22.1

Known cancer genes

Yes

Protein products

cDNA FLJ76440, highly similar to Homo sapiens TRIAD3 protein (TRIAD3), transcript variant 1, mRNA

E3 ubiquitin-protein ligase RNF216

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:21698
MIM:609948
Ensembl:ENSG00000011275
HPRD:15550
RefSeq Genomic nucleotide accession:AC_000050
RefSeq Genomic nucleotide gi:89161211

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0005515

protein binding

GO:0005634

nucleus

GO:0005730

nucleolus

GO:0005737

cytoplasm

GO:0006915

apoptosis

GO:0008270

zinc ion binding

GO:0016874

ligase activity

GO:0032648

regulation of interferon-beta production

GO:0043161

proteasomal ubiquitin-dependent protein catabolic process

GO:0044419

interspecies interaction between organisms

GO:0046872

metal ion binding

GO:0050691

regulation of defense response to virus by host

GO:0070936

protein K48-linked ubiquitination