HuLG010188

Entrez Gene ID

54658

Official Gene Symbol

UGT1A1

Synonyms

BILIQTL1|GNT1|HUGNBR1|UDPGT|UDPGT_1N1|UGT1|UGT1A

Gene name

UDP glucuronosyltransferase 1 family, polypeptide A1

Gene Type

protein-coding

Chromosome

2

Genomics Location

2q37

Known cancer genes

Yes

Protein products

HCG2039726, isoform CRA a

Bilirubin UDP-glucronosyltrasferase 1-1

UDP-glucuronosyltransferase

UDP-glucuronosyltransferase 1-1

Related liver disease name

Hepatitis

Viral hepatitis

Hepatitis A

Hepatitis B

Hepatitis C

Chronic hepatitis C

Hepatitis D

Hepatitis E

Chronic hepatitis

Autoimmune hepatitis

Drug-induced hepatitis

Hepatocellular carcinoma

Gilbert syndrome

Lucey-Driscoll syndrome

Arias syndrome

Breast milk jaundice

Crigler-Najjar syndrome, type 1

Database cross reference

HGNC:12530
MIM:191740
Ensembl:ENSG00000241635
HPRD:08933
RefSeq Genomic nucleotide accession:AC_000045
RefSeq Genomic nucleotide gi:89161198

Yes/No

Yes

Evidence

Translational level from literatures

Quality score

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net

Quality score

GO annotation

GO:0001889

liver development

GO:0001972

retinoic acid binding

GO:0004857

enzyme inhibitor activity

GO:0005496

steroid binding

GO:0005783

endoplasmic reticulum

GO:0005789

endoplasmic reticulum membrane

GO:0005792

microsome

GO:0005887

integral to plasma membrane

GO:0006778

porphyrin metabolic process

GO:0006789

bilirubin conjugation

GO:0006805

xenobiotic metabolic process

GO:0007584

response to nutrient

GO:0007586

digestion

GO:0008152

metabolic process

GO:0008202

steroid metabolic process

GO:0008210

estrogen metabolic process

GO:0009812

flavonoid metabolic process

GO:0014070

response to organic cyclic compound

GO:0015020

glucuronosyltransferase activity

GO:0016020

membrane

GO:0017144

drug metabolic process

GO:0019899

enzyme binding

GO:0031100

organ regeneration

GO:0032496

response to lipopolysaccharide

GO:0032870

cellular response to hormone stimulus

GO:0042167

heme catabolic process

GO:0042493

response to drug

GO:0042573

retinoic acid metabolic process

GO:0042594

response to starvation

GO:0042803

protein homodimerization activity

GO:0043086

negative regulation of catalytic activity

GO:0045939

negative regulation of steroid metabolic process

GO:0046483

heterocycle metabolic process

GO:0046982

protein heterodimerization activity

GO:0048545

response to steroid hormone stimulus

GO:0051552

flavone metabolic process

GO:0070980

biphenyl catabolic process

GO:0071361

cellular response to ethanol

GO:0071385

cellular response to glucocorticoid stimulus