HuLG010629

Entrez Gene ID

55256

Official Gene Symbol

ADI1

Synonyms

APL1|ARD|FLJ10913|MTCBP1|NiNARD|SIPL

Gene name

acireductone dioxygenase 1

Gene Type

protein-coding

Chromosome

2

Genomics Location

2p25.3

Known cancer genes

Yes

Protein products

1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:30576
MIM:613400
Ensembl:ENSG00000182551
HPRD:17607
RefSeq Genomic nucleotide accession:AC_000045
RefSeq Genomic nucleotide gi:89161198

HCC significant genes

Yes/No

Yes

Evidence

EHCO

Quality score

GO annotation

GO:0005515

protein binding

GO:0005634

nucleus

GO:0005737

cytoplasm

GO:0005886

plasma membrane

GO:0008652

cellular amino acid biosynthetic process

GO:0009086

methionine biosynthetic process

GO:0010308

acireductone dioxygenase (Ni2+-requiring) activity

GO:0016491

oxidoreductase activity

GO:0019509

L-methionine salvage from methylthioadenosine

GO:0046872

metal ion binding

GO:0055114

oxidation-reduction process