HuLG010916

Entrez Gene ID

55743

Official Gene Symbol

CHFR

Synonyms

FLJ10796|FLJ33629|RNF116|RNF196

Gene name

checkpoint with forkhead and ring finger domains

Gene Type

protein-coding

Chromosome

12

Genomics Location

12q24.33

Known cancer genes

Yes

Protein products

E3 ubiquitin-protein ligase CHFR

Related liver disease name

Intrahepatic cholangiocarcinoma

Hepatocellular carcinoma

Database cross reference

HGNC:20455
MIM:605209
Ensembl:ENSG00000072609
RefSeq Genomic nucleotide accession:AC_000055
RefSeq Genomic nucleotide gi:89161189

GO annotation

GO:0000166

nucleotide binding

GO:0000209

protein polyubiquitination

GO:0004842

ubiquitin-protein ligase activity

GO:0005515

protein binding

GO:0005634

nucleus

GO:0007049

cell cycle

GO:0007067

mitosis

GO:0007093

mitotic cell cycle checkpoint

GO:0008270

zinc ion binding

GO:0016605

PML body

GO:0016874

ligase activity

GO:0019941

modification-dependent protein catabolic process

GO:0046872

metal ion binding

GO:0051301

cell division