Gene basic information
| LiverAtlas Gene ID |
HuLG011217 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
SPHK2 |
|
Gene name |
sphingosine kinase 2 |
|
Gene Type |
protein-coding |
|
Chromosome |
19 |
|
Genomics Location |
19q13.2 |
|
Known cancer genes |
Yes |
|
Protein products |
cDNA FLJ59429, highly similar to Sphingosine kinase 2 (EC 2.7.1.-) |
|
Related liver disease name |
|
|
Database cross reference |
HGNC:18859
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0000166 |
nucleotide binding |
|
GO:0001568 |
blood vessel development |
|
GO:0004143 |
diacylglycerol kinase activity |
|
GO:0005515 |
protein binding |
|
GO:0005524 |
ATP binding |
|
GO:0005624 |
membrane fraction |
|
GO:0005737 |
cytoplasm |
|
GO:0005765 |
lysosomal membrane |
|
GO:0005829 |
cytosol |
|
GO:0006665 |
sphingolipid metabolic process |
|
GO:0006669 |
sphinganine-1-phosphate biosynthetic process |
|
GO:0006670 |
sphingosine metabolic process |
|
GO:0006916 |
anti-apoptosis |
|
GO:0007205 |
activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway |
|
GO:0007420 |
brain development |
|
GO:0008283 |
cell proliferation |
|
GO:0008284 |
positive regulation of cell proliferation |
|
GO:0008481 |
sphinganine kinase activity |
|
GO:0016020 |
membrane |
|
GO:0016740 |
transferase activity |
|
GO:0017016 |
Ras GTPase binding |
|
GO:0017050 |
D-erythro-sphingosine kinase activity |
