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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG011386

Entrez Gene ID

57142

Official Gene Symbol

RTN4

Synonyms

ASY|NI220/250|NOGO|NOGONA|NOGOC|NSP|NSPNCL|Nbla00271|Nbla10545|NogoNB|NogoNC|RTNNX|RTN4NA|RTN4NB1|RTN4NB2|RTN4NC

Gene name

reticulon 4

Gene Type

protein-coding

Chromosome

2

Genomics Location

2p16.3

Known cancer genes

Yes

Protein products

NOGO-A

NOGO-A

Putative uncharacterized protein RTN4

Putative uncharacterized protein RTN4

Putative uncharacterized protein RTN4

RTN4 protein

RTN4

RTN4

RNT4

Reticulon-4

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:14085
MIM:604475
Ensembl:ENSG00000115310
HPRD:07259
RefSeq Genomic nucleotide accession:AC_000045
RefSeq Genomic nucleotide gi:89161198

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

OncoDB

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0001525

angiogenesis

GO:0005515

protein binding

GO:0005635

nuclear envelope

GO:0005737

cytoplasm

GO:0005783

endoplasmic reticulum

GO:0005789

endoplasmic reticulum membrane

GO:0005886

plasma membrane

GO:0006915

apoptosis

GO:0007413

axonal fasciculation

GO:0007568

aging

GO:0014823

response to activity

GO:0016021

integral to membrane

GO:0019987

negative regulation of anti-apoptosis

GO:0021553

olfactory nerve development

GO:0021801

cerebral cortex radial glia guided migration

GO:0030176

integral to endoplasmic reticulum membrane

GO:0030308

negative regulation of cell growth

GO:0030334

regulation of cell migration

GO:0030517

negative regulation of axon extension

GO:0032403

protein complex binding

GO:0033603

positive regulation of dopamine secretion

GO:0042981

regulation of apoptosis

GO:0043005

neuron projection

GO:0043025

neuronal cell body

GO:0043209

myelin sheath

GO:0043234

protein complex

GO:0045665

negative regulation of neuron differentiation

GO:0045687

positive regulation of glial cell differentiation

GO:0048011

nerve growth factor receptor signaling pathway

GO:0048679

regulation of axon regeneration

GO:0048709

oligodendrocyte differentiation

GO:0050770

regulation of axonogenesis

GO:0050771

negative regulation of axonogenesis

GO:0051930

regulation of sensory perception of pain

GO:0060317

cardiac epithelial to mesenchymal transition

GO:0070571

negative regulation of neuron projection regeneration

GO:0071786

endoplasmic reticulum tubular network organization

GO:2000172

regulation of branching morphogenesis of a nerve