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Gene basic information

LiverAtlas Gene ID

HuLG011662

Entrez Gene ID

57680

Official Gene Symbol

CHD8

Synonyms

DKFZp686N17164|HELSNF1|KIAA1564

Gene name

chromodomain helicase DNA binding protein 8

Gene Type

protein-coding

Chromosome

14

Genomics Location

14q11.2

Known cancer genes

Yes

Protein products

Chromodomain-helicase-DNA-binding protein 8

Database cross reference

HGNC:20153
MIM:610528
Ensembl:ENSG00000100888
HPRD:16712
RefSeq Genomic nucleotide accession:AC_000057
RefSeq Genomic nucleotide gi:89161192

 

Ontology annotation

GO ID

GO annotation

GO:0000166

nucleotide binding

GO:0002039

p53 binding

GO:0003677

DNA binding

GO:0003678

DNA helicase activity

GO:0005515

protein binding

GO:0005524

ATP binding

GO:0005634

nucleus

GO:0006355

regulation of transcription, DNA-dependent

GO:0008013

beta-catenin binding

GO:0008094

DNA-dependent ATPase activity

GO:0016568

chromatin modification

GO:0016817

hydrolase activity, acting on acid anhydrides

GO:0030178

negative regulation of Wnt receptor signaling pathway

GO:0035064

methylated histone residue binding

GO:0042393

histone binding

GO:0043044

ATP-dependent chromatin remodeling

GO:0043234

protein complex

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

GO:0045945

positive regulation of transcription from RNA polymerase III promoter

GO:0060070

canonical Wnt receptor signaling pathway

GO:0071339

MLL1 complex