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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG011790

Entrez Gene ID

59067

Official Gene Symbol

IL21

Synonyms

ILN21|Za11

Gene name

interleukin 21

Gene Type

protein-coding

Chromosome

4

Genomics Location

4q26-q27

Protein products

Interleukin-21

Related liver disease name

Hepatitis

Hepatitis A

Hepatitis B

Hepatitis C

Hepatitis D

Hepatitis E

Hepatocellular carcinoma

Database cross reference

HGNC:6005
MIM:605384
Ensembl:ENSG00000138684
HPRD:05650
RefSeq Genomic nucleotide accession:AC_000047
RefSeq Genomic nucleotide gi:89161206

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0002729

positive regulation of natural killer cell cytokine production

GO:0005125

cytokine activity

GO:0005126

cytokine receptor binding

GO:0005134

interleukin-2 receptor binding

GO:0005576

extracellular region

GO:0005615

extracellular space

GO:0006955

immune response

GO:0007165

signal transduction

GO:0032733

positive regulation of interleukin-10 production

GO:0032740

positive regulation of interleukin-17 production

GO:0032825

positive regulation of natural killer cell differentiation

GO:0034105

positive regulation of tissue remodeling

GO:0042102

positive regulation of T cell proliferation

GO:0045078

positive regulation of interferon-gamma biosynthetic process

GO:0045954

positive regulation of natural killer cell mediated cytotoxicity

GO:0048469

cell maturation

GO:0050729

positive regulation of inflammatory response