Gene basic information
| LiverAtlas Gene ID |
HuLG011800 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
SIGIRR |
|
Synonyms |
MGC110992|TIR8 |
|
Gene name |
single immunoglobulin and toll-interleukin 1 receptor (TIR) domain |
|
Gene Type |
protein-coding |
|
Chromosome |
11 |
|
Genomics Location |
11p15.5 |
|
Protein products |
|
|
Related liver disease name |
|
|
Database cross reference |
HGNC:30575
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
HCC.net |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0001960 |
negative regulation of cytokine-mediated signaling pathway |
|
GO:0004888 |
transmembrane receptor activity |
|
GO:0005515 |
protein binding |
|
GO:0006953 |
acute-phase response |
|
GO:0007165 |
signal transduction |
|
GO:0016020 |
membrane |
|
GO:0016021 |
integral to membrane |
|
GO:0031665 |
negative regulation of lipopolysaccharide-mediated signaling pathway |
|
GO:0043433 |
negative regulation of sequence-specific DNA binding transcription factor activity |
|
GO:0045079 |
negative regulation of chemokine biosynthetic process |
|
GO:0045087 |
innate immune response |
