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Gene basic information

LiverAtlas Gene ID

HuLG011973

Entrez Gene ID

64135

Official Gene Symbol

IFIH1

Synonyms

Hlcd|IDDM19|MDAN5|MDA5|MGC133047

Gene name

interferon induced with helicase C domain 1

Gene Type

protein-coding

Chromosome

2

Genomics Location

2q24

Known cancer genes

Yes

Protein products

Interferon-induced helicase C domain-containing protein 1

Putative uncharacterized protein MDA5

Putative uncharacterized protein MDA5

Related liver disease name

Hepatitis C

Database cross reference

HGNC:18873
MIM:606951
Ensembl:ENSG00000115267
HPRD:09507
RefSeq Genomic nucleotide accession:AC_000045
RefSeq Genomic nucleotide gi:89161198

 

Ontology annotation

GO ID

GO annotation

GO:0000166

nucleotide binding

GO:0003677

DNA binding

GO:0003725

double-stranded RNA binding

GO:0004386

helicase activity

GO:0005515

protein binding

GO:0005524

ATP binding

GO:0005622

intracellular

GO:0005634

nucleus

GO:0005737

cytoplasm

GO:0005829

cytosol

GO:0008270

zinc ion binding

GO:0009597

detection of virus

GO:0016817

hydrolase activity, acting on acid anhydrides

GO:0032480

negative regulation of type I interferon production

GO:0032727

positive regulation of interferon-alpha production

GO:0032728

positive regulation of interferon-beta production

GO:0042981

regulation of apoptosis

GO:0043021

ribonucleoprotein binding

GO:0044419

interspecies interaction between organisms

GO:0045087

innate immune response

GO:0046872

metal ion binding