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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG012067

Entrez Gene ID

64581

Official Gene Symbol

CLEC7A

Synonyms

BGR|CANDF4|CLECSF12|DECTIN1

Gene name

C-type lectin domain family 7, member A

Gene Type

protein-coding

Chromosome

12

Genomics Location

12p13.2

Known cancer genes

Yes

Protein products

C-type lectin domain family 7 member A

Putative uncharacterized protein DKFZp686L24211

DF4

C-type lectin domain family 7, member A

Related liver disease name

Hepatitis

Hepatitis A

Hepatitis B

Hepatitis C

Hepatitis D

Hepatitis E

Hepatocellular carcinoma

Database cross reference

HGNC:14558
MIM:606264
Ensembl:ENSG00000172243
HPRD:08396
RefSeq Genomic nucleotide accession:AC_000055
RefSeq Genomic nucleotide gi:89161189

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

HCC.net

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0001846

opsonin binding

GO:0001874

1,3-beta-D-glucan receptor activity

GO:0001879

detection of yeast

GO:0002221

pattern recognition receptor signaling pathway

GO:0002238

response to molecule of fungal origin

GO:0002752

cell surface pattern recognition receptor signaling pathway

GO:0005488

binding

GO:0005529

sugar binding

GO:0005737

cytoplasm

GO:0006910

phagocytosis, recognition

GO:0006911

phagocytosis, engulfment

GO:0006954

inflammatory response

GO:0008037

cell recognition

GO:0008329

pattern recognition receptor activity

GO:0009756

carbohydrate mediated signaling

GO:0009897

external side of plasma membrane

GO:0016020

membrane

GO:0016021

integral to membrane

GO:0016337

cell-cell adhesion

GO:0032760

positive regulation of tumor necrosis factor production

GO:0042110

T cell activation

GO:0042287

MHC protein binding

GO:0042832

defense response to protozoan

GO:0045087

innate immune response

GO:0050766

positive regulation of phagocytosis