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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG012220

Entrez Gene ID

65125

Official Gene Symbol

WNK1

Synonyms

HSAN2|HSN2|KDP|KIAA0344|MGC163339|MGC163341|PRKWNK1|PSK|p65

Gene name

WNK lysine deficient protein kinase 1

Gene Type

protein-coding

Chromosome

12

Genomics Location

12p13.3

Known cancer genes

Yes

Protein products

WNK1 protein

WNK lysine deficient protein kinase 1, isoform CRA b

Serine/threonine-protein kinase WNK1

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:14540
MIM:605232
Ensembl:ENSG00000060237
HPRD:05570
RefSeq Genomic nucleotide accession:AC_000055
RefSeq Genomic nucleotide gi:89161189

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0000166

nucleotide binding

GO:0003084

positive regulation of systemic arterial blood pressure

GO:0003674

molecular function

GO:0004674

protein serine/threonine kinase activity

GO:0004860

protein kinase inhibitor activity

GO:0005515

protein binding

GO:0005524

ATP binding

GO:0005575

cellular component

GO:0005625

soluble fraction

GO:0005737

cytoplasm

GO:0006468

protein phosphorylation

GO:0006811

ion transport

GO:0007243

intracellular protein kinase cascade

GO:0042598

vesicular fraction

GO:0048666

neuron development

GO:0050794

regulation of cellular process