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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG012242

Entrez Gene ID

65985

Official Gene Symbol

AACS

Synonyms

ACSF1|FLJ12389|FLJ41251|SURN5

Gene name

acetoacetyl-CoA synthetase

Gene Type

protein-coding

Chromosome

12

Genomics Location

12q24.31

Known cancer genes

Yes

Protein products

Acetoacetyl-CoA synthetase

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:21298
Ensembl:ENSG00000081760
HPRD:12391
RefSeq Genomic nucleotide accession:AC_000055
RefSeq Genomic nucleotide gi:89161189


Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0000166

nucleotide binding

GO:0001889

liver development

GO:0005524

ATP binding

GO:0005737

cytoplasm

GO:0005829

cytosol

GO:0006629

lipid metabolic process

GO:0006631

fatty acid metabolic process

GO:0007584

response to nutrient

GO:0010243

response to organic nitrogen

GO:0014074

response to purine-containing compound

GO:0016874

ligase activity

GO:0030729

acetoacetate-CoA ligase activity

GO:0032024

positive regulation of insulin secretion

GO:0034201

response to oleic acid

GO:0042493

response to drug

GO:0042594

response to starvation

GO:0045471

response to ethanol

GO:0047760

butyrate-CoA ligase activity

GO:0050872

white fat cell differentiation

GO:0060612

adipose tissue development

GO:0071333

cellular response to glucose stimulus

GO:0071394

cellular response to testosterone stimulus

GO:0071397

cellular response to cholesterol