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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG012903

Entrez Gene ID

80351

Official Gene Symbol

TNKS2

Synonyms

PARPN5b|PARPN5c|PARP5B|PARP5C|TANK2|TNKL|pART6

Gene name

tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2

Gene Type

protein-coding

Chromosome

10

Genomics Location

10q23.3

Known cancer genes

Yes

Protein products

Tankyrase-2

Related liver disease name

Hepatitis

Hepatitis A

Hepatitis B

Hepatitis C

Hepatitis D

Hepatitis E

Hepatocellular carcinoma

Database cross reference

HGNC:15677
MIM:607128
Ensembl:ENSG00000107854
HPRD:06182
RefSeq Genomic nucleotide accession:AC_000053
RefSeq Genomic nucleotide gi:89161186

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0000139

Golgi membrane

GO:0000209

protein polyubiquitination

GO:0000242

pericentriolar material

GO:0000784

nuclear chromosome, telomeric region

GO:0003950

NAD+ ADP-ribosyltransferase activity

GO:0005515

protein binding

GO:0005634

nucleus

GO:0005635

nuclear envelope

GO:0005694

chromosome

GO:0005737

cytoplasm

GO:0005792

microsome

GO:0005794

Golgi apparatus

GO:0006471

protein ADP-ribosylation

GO:0016020

membrane

GO:0016757

transferase activity, transferring glycosyl groups

GO:0032212

positive regulation of telomere maintenance via telomerase

GO:0048471

perinuclear region of cytoplasm

GO:0070198

protein localization to chromosome, telomeric region

GO:0070213

protein auto-ADP-ribosylation

GO:0090263

positive regulation of canonical Wnt receptor signaling pathway