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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG013082

Entrez Gene ID

81847

Official Gene Symbol

RNF146

Synonyms

DKFZp434O1427|RP3N351K20.1|dJ351K20.1

Gene name

ring finger protein 146

Gene Type

protein-coding

Chromosome

6

Genomics Location

6q22.1-q22.33

Known cancer genes

Yes

Protein products

E3 ubiquitin-protein ligase RNF146

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:21336
MIM:612137
Ensembl:ENSG00000118518
RefSeq Genomic nucleotide accession:AC_000049
RefSeq Genomic nucleotide gi:89161209


Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0004842

ubiquitin-protein ligase activity

GO:0005515

protein binding

GO:0005829

cytosol

GO:0008270

zinc ion binding

GO:0042787

protein ubiquitination involved in ubiquitin-dependent protein catabolic process

GO:0046872

metal ion binding

GO:0051865

protein autoubiquitination

GO:0070936

protein K48-linked ubiquitination

GO:0072572

poly-ADP-D-ribose binding

GO:0090263

positive regulation of canonical Wnt receptor signaling pathway