Gene basic information
| LiverAtlas Gene ID |
HuLG014129 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
MTDH |
|
Synonyms |
3D3|AEGN1|AEG1|LYRIC|LYRIC/3D3 |
|
Gene name |
metadherin |
|
Gene Type |
protein-coding |
|
Chromosome |
8 |
|
Genomics Location |
8q22.1 |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Related liver disease name |
|
|
Database cross reference |
HGNC:29608
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0000122 |
negative regulation of transcription from RNA polymerase II promoter |
|
GO:0001085 |
RNA polymerase II transcription factor binding |
|
GO:0003713 |
transcription coactivator activity |
|
GO:0005515 |
protein binding |
|
GO:0005634 |
nucleus |
|
GO:0005730 |
nucleolus |
|
GO:0005737 |
cytoplasm |
|
GO:0005783 |
endoplasmic reticulum |
|
GO:0005789 |
endoplasmic reticulum membrane |
|
GO:0005923 |
tight junction |
|
GO:0010508 |
positive regulation of autophagy |
|
GO:0016020 |
membrane |
|
GO:0016021 |
integral to membrane |
|
GO:0016324 |
apical plasma membrane |
|
GO:0016604 |
nuclear body |
|
GO:0030054 |
cell junction |
|
GO:0031663 |
lipopolysaccharide-mediated signaling pathway |
|
GO:0031965 |
nuclear membrane |
|
GO:0043066 |
negative regulation of apoptosis |
|
GO:0043123 |
positive regulation of I-kappaB kinase/NF-kappaB cascade |
|
GO:0045766 |
positive regulation of angiogenesis |
|
GO:0046581 |
intercellular canaliculus |
|
GO:0048471 |
perinuclear region of cytoplasm |
|
GO:0051059 |
NF-kappaB binding |
|
GO:0051092 |
positive regulation of NF-kappaB transcription factor activity |
|
GO:0051897 |
positive regulation of protein kinase B signaling cascade |
|
GO:0070830 |
tight junction assembly |
