HuLG015077

Entrez Gene ID

133396

Official Gene Symbol

IL31RA

Synonyms

CRL|CRL3|GLMNR|GLMR|GPL|ILN31RA|MGC125346|PRO21384|hGLMNR

Gene name

interleukin 31 receptor A

Gene Type

protein-coding

Chromosome

5

Genomics Location

5q11.2

Known cancer genes

Yes

Protein products

Interleukin-31 receptor subunit alpha

Related liver disease name

Hepatitis

Hepatitis A

Hepatitis B

Hepatitis C

Hepatitis D

Hepatitis E

Database cross reference

HGNC:18969
MIM:609510
Ensembl:ENSG00000164509
HPRD:17145
RefSeq Genomic nucleotide accession:AC_000048
RefSeq Genomic nucleotide gi:89161208

GO annotation

GO:0000165

MAPKKK cascade

GO:0003713

transcription coactivator activity

GO:0004872

receptor activity

GO:0004896

cytokine receptor activity

GO:0005886

plasma membrane

GO:0006916

anti-apoptosis

GO:0006952

defense response

GO:0007169

transmembrane receptor protein tyrosine kinase signaling pathway

GO:0007259

JAK-STAT cascade

GO:0008284

positive regulation of cell proliferation

GO:0016021

integral to membrane

GO:0019221

cytokine-mediated signaling pathway

GO:0019901

protein kinase binding

GO:0019955

cytokine binding

GO:0030224

monocyte differentiation

GO:0030225

macrophage differentiation

GO:0042517

positive regulation of tyrosine phosphorylation of Stat3 protein

GO:0042523

positive regulation of tyrosine phosphorylation of Stat5 protein

GO:0042592

homeostatic process

GO:0043031

negative regulation of macrophage activation

GO:0045893

positive regulation of transcription, DNA-dependent