HuLG015304

Entrez Gene ID

142678

Official Gene Symbol

MIB2

Synonyms

FLJ20648|FLJ39787|FLJ41406|ZZANK1|ZZZ5

Gene name

mindbomb homolog 2 (Drosophila)

Gene Type

protein-coding

Chromosome

1

Genomics Location

1p36.33

Known cancer genes

Yes

Protein products

cDNA FLJ46290 fis, clone TESTI4032913, highly similar to Ubiquitin ligase protein MIB2 (EC 6.3.2.-)

cDNA FLJ58785, highly similar to Ubiquitin ligase protein MIB2 (EC 6.3.2.-)

Uncharacterized protein

Uncharacterized protein

Uncharacterized protein

Uncharacterized protein

Uncharacterized protein

E3 ubiquitin-protein ligase MIB2

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:30577
MIM:611141
Ensembl:ENSG00000197530
HPRD:15905
RefSeq Genomic nucleotide accession:AC_000044
RefSeq Genomic nucleotide gi:89161184

HCC significant genes

Yes/No

Yes

Evidence

EHCO

Quality score

GO annotation

GO:0003779

actin binding

GO:0004842

ubiquitin-protein ligase activity

GO:0004871

signal transducer activity

GO:0005737

cytoplasm

GO:0005768

endosome

GO:0007165

signal transduction

GO:0007219

Notch signaling pathway

GO:0008270

zinc ion binding

GO:0016874

ligase activity

GO:0043123

positive regulation of I-kappaB kinase/NF-kappaB cascade

GO:0046872

metal ion binding