HuLG015557

Entrez Gene ID

149233

Official Gene Symbol

IL23R

Gene name

interleukin 23 receptor

Gene Type

protein-coding

Chromosome

1

Genomics Location

1p31.3

Protein products

Interleukin 23 receptor

Interleukin 23 receptor

Interleukin-23 receptor

Related liver disease name

Liver fibrosis and liver cirrhosis

Biliary cirrhosis

Database cross reference

HGNC:19100
MIM:607562
Ensembl:ENSG00000162594
HPRD:16249
RefSeq Genomic nucleotide accession:AC_000044
RefSeq Genomic nucleotide gi:89161184

GO annotation

GO:0001916

positive regulation of T cell mediated cytotoxicity

GO:0002230

positive regulation of defense response to virus by host

GO:0002827

positive regulation of T-helper 1 type immune response

GO:0004872

receptor activity

GO:0005143

interleukin-12 receptor binding

GO:0005886

plasma membrane

GO:0006954

inflammatory response

GO:0010535

positive regulation of activation of JAK2 kinase activity

GO:0016021

integral to membrane

GO:0032496

response to lipopolysaccharide

GO:0032693

negative regulation of interleukin-10 production

GO:0032725

positive regulation of granulocyte macrophage colony-stimulating factor production

GO:0032729

positive regulation of interferon-gamma production

GO:0032735

positive regulation of interleukin-12 production

GO:0032740

positive regulation of interleukin-17 production

GO:0032819

positive regulation of natural killer cell proliferation

GO:0034341

response to interferon-gamma

GO:0042019

interleukin-23 binding

GO:0042020

interleukin-23 receptor activity

GO:0042102

positive regulation of T cell proliferation

GO:0042104

positive regulation of activated T cell proliferation

GO:0042510

regulation of tyrosine phosphorylation of Stat1 protein

GO:0042517

positive regulation of tyrosine phosphorylation of Stat3 protein

GO:0042520

positive regulation of tyrosine phosphorylation of Stat4 protein

GO:0042523

positive regulation of tyrosine phosphorylation of Stat5 protein

GO:0043382

positive regulation of memory T cell differentiation

GO:0045672

positive regulation of osteoclast differentiation

GO:0050829

defense response to Gram-negative bacterium

GO:0051135

positive regulation of NK T cell activation

GO:0072536

interleukin-23 receptor complex

GO:2000318

positive regulation of T-helper 17 type immune response

GO:2000330

positive regulation of T-helper 17 cell lineage commitment