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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG015706

Entrez Gene ID

152831

Official Gene Symbol

KLB

Synonyms

BKL|MGC142213

Gene name

klotho beta

Gene Type

protein-coding

Chromosome

4

Genomics Location

4p14

Known cancer genes

Yes

Protein products

cDNA FLJ50094, highly similar to Beta klotho

KLB protein

Beta-klotho

KLB protein

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:15527
MIM:611135
Ensembl:ENSG00000134962
HPRD:14097
RefSeq Genomic nucleotide accession:AC_000047
RefSeq Genomic nucleotide gi:89161206

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

HCC.net

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0003824

catalytic activity

GO:0004553

hydrolase activity, hydrolyzing O-glycosyl compounds

GO:0005886

plasma membrane

GO:0005975

carbohydrate metabolic process

GO:0008284

positive regulation of cell proliferation

GO:0016021

integral to membrane

GO:0017134

fibroblast growth factor binding

GO:0043169

cation binding

GO:0090080

positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway