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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG015963

Entrez Gene ID

164656

Official Gene Symbol

TMPRSS6

Synonyms

IRIDA

Gene name

transmembrane protease, serine 6

Gene Type

protein-coding

Chromosome

22

Genomics Location

22q12.3

Known cancer genes

Yes

Protein products

Uncharacterized protein

Transmembrane protease serine 6

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:16517
MIM:609862
Ensembl:ENSG00000187045
HPRD:10270
RefSeq Genomic nucleotide accession:AC_000065
RefSeq Genomic nucleotide gi:89161202

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

HCC.net

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0001525

angiogenesis

GO:0004252

serine-type endopeptidase activity

GO:0005886

plasma membrane

GO:0006508

proteolysis

GO:0008233

peptidase activity

GO:0016021

integral to membrane

GO:0030198

extracellular matrix organization

GO:0035556

intracellular signal transduction

GO:0042730

fibrinolysis