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Gene basic information

LiverAtlas Gene ID

HuLG017504

Entrez Gene ID

353376

Official Gene Symbol

TICAM2

Synonyms

MGC129876|MGC129877|TICAMN2|TIRAP3|TIRP|TRAM

Gene name

toll-like receptor adaptor molecule 2

Gene Type

protein-coding

Chromosome

5

Genomics Location

5q23.1

Protein products

TIR domain-containing adapter molecule 2

Database cross reference

HGNC:21354
MIM:608321
Ensembl:ENSG00000243414
Ensembl:ENSG00000251201
HPRD:16313
RefSeq Genomic nucleotide accession:AC_000048
RefSeq Genomic nucleotide gi:89161208

 

Ontology annotation

GO ID

GO annotation

GO:0002224

toll-like receptor signaling pathway

GO:0002755

MyD88-dependent toll-like receptor signaling pathway

GO:0002756

MyD88-independent toll-like receptor signaling pathway

GO:0004871

signal transducer activity

GO:0004888

transmembrane receptor activity

GO:0005515

protein binding

GO:0005737

cytoplasm

GO:0005794

Golgi apparatus

GO:0005886

plasma membrane

GO:0006954

inflammatory response

GO:0007165

signal transduction

GO:0007249

I-kappaB kinase/NF-kappaB cascade

GO:0008063

Toll signaling pathway

GO:0031224

intrinsic to membrane

GO:0034130

toll-like receptor 1 signaling pathway

GO:0034134

toll-like receptor 2 signaling pathway

GO:0034142

toll-like receptor 4 signaling pathway

GO:0043123

positive regulation of I-kappaB kinase/NF-kappaB cascade

GO:0045087

innate immune response