HuLG019732

Entrez Gene ID

3559

Official Gene Symbol

IL2RA

Synonyms

CD25|IDDM10|IL2R|TCGFR

Gene name

interleukin 2 receptor, alpha

Gene Type

protein-coding

Chromosome

10

Genomics Location

10p15-p14

Protein products

Interleukin-2 receptor subunit alpha

Related liver disease name

Hepatitis

Liver fibrosis and liver cirrhosis

Hepatitis A

Hepatitis B

Chronic hepatitis B

Hepatitis C

Hepatitis D

Hepatitis E

Chronic hepatitis

Database cross reference

HGNC:6008
MIM:147730
Ensembl:ENSG00000134460
HPRD:00986
RefSeq Genomic nucleotide accession:AC_000053
RefSeq Genomic nucleotide gi:89161186
http://www.ncbi.nlm.nih.gov/nuccore/AC_000142?report=genbank

GO annotation

GO:0002437

inflammatory response to antigenic stimulus

GO:0004872

receptor activity

GO:0004911

interleukin-2 receptor activity

GO:0005886

plasma membrane

GO:0006915

apoptosis

GO:0006924

activation-induced cell death of T cells

GO:0006955

immune response

GO:0007166

cell surface receptor linked signaling pathway

GO:0008144

drug binding

GO:0008283

cell proliferation

GO:0009897

external side of plasma membrane

GO:0016021

integral to membrane

GO:0042104

positive regulation of activated T cell proliferation

GO:0042130

negative regulation of T cell proliferation

GO:0043065

positive regulation of apoptosis

GO:0045582

positive regulation of T cell differentiation

GO:0046013

regulation of T cell homeostatic proliferation

GO:0050687

negative regulation of defense response to virus

GO:0050728

negative regulation of inflammatory response

GO:0050777

negative regulation of immune response