HuLG019744

Entrez Gene ID

3579

Official Gene Symbol

IL8RB

Synonyms

CD182|CDw128b|CMKAR2|IL8R2|IL8RA|IL8RB

Gene name

chemokine (C-X-C motif) receptor 2

Gene Type

protein-coding

Chromosome

2

Genomics Location

2q35

Protein products

C-X-C chemokine receptor type 2

Interleukin 8 receptor, beta

Related liver disease name

Hepatitis C

Database cross reference

HGNC:6027
MIM:146928
Ensembl:ENSG00000180871
HPRD:00907
RefSeq Genomic nucleotide accession:AC_000045
RefSeq Genomic nucleotide gi:89161198
http://www.ncbi.nlm.nih.gov/nuccore/AC_000134?report=genbank

GO annotation

GO:0002407

dendritic cell chemotaxis

GO:0004871

signal transducer activity

GO:0004872

receptor activity

GO:0004918

interleukin-8 receptor activity

GO:0004930

G-protein coupled receptor activity

GO:0005622

intracellular

GO:0005886

plasma membrane

GO:0005887

integral to plasma membrane

GO:0006935

chemotaxis

GO:0006954

inflammatory response

GO:0006968

cellular defense response

GO:0007165

signal transduction

GO:0007166

cell surface receptor linked signaling pathway

GO:0007200

activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger

GO:0008284

positive regulation of cell proliferation

GO:0009986

cell surface

GO:0016020

membrane

GO:0016494

C-X-C chemokine receptor activity

GO:0019959

interleukin-8 binding

GO:0030593

neutrophil chemotaxis

GO:0042119

neutrophil activation

GO:0042629

mast cell granule