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Gene basic information

LiverAtlas Gene ID

HuLG019754

Entrez Gene ID

57506

Official Gene Symbol

VISA

Synonyms

CARDIF|DKFZp547C224|DKFZp666M015|FLJ27482|FLJ31698|FLJ35386|FLJ38051|FLJ41962|IPS-1|IPS1|KIAA1271|MGC3260|VISA

Gene name

mitochondrial antiviral signaling protein

Gene Type

protein-coding

Chromosome

20

Genomics Location

20p13

Protein products

Mitochondrial antiviral-signaling protein

Related liver disease name

Chronic hepatitis C

Database cross reference

HGNC:29233
MIM:609676
Ensembl:ENSG00000088888
HPRD:13847
RefSeq Genomic nucleotide accession:-
RefSeq Genomic nucleotide gi:-
http://www.ncbi.nlm.nih.gov/nuccore/AC_000063?report=genbank

 

Ontology annotation

GO ID

GO annotation

GO:0001934

positive regulation of protein phosphorylation

GO:0002218

activation of innate immune response

GO:0002230

positive regulation of defense response to virus by host

GO:0004871

signal transducer activity

GO:0005515

protein binding

GO:0005739

mitochondrion

GO:0005741

mitochondrial outer membrane

GO:0007165

signal transduction

GO:0009615

response to virus

GO:0016020

membrane

GO:0016021

integral to membrane

GO:0019901

protein kinase binding

GO:0032480

negative regulation of type I interferon production

GO:0032727

positive regulation of interferon-alpha production

GO:0032728

positive regulation of interferon-beta production

GO:0032757

positive regulation of interleukin-8 production

GO:0032760

positive regulation of tumor necrosis factor production

GO:0033160

positive regulation of protein import into nucleus, translocation

GO:0042742

defense response to bacterium

GO:0042993

positive regulation of transcription factor import into nucleus

GO:0043123

positive regulation of I-kappaB kinase/NF-kappaB cascade

GO:0044419

interspecies interaction between organisms

GO:0045087

innate immune response

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

GO:0050700

CARD domain binding

GO:0051091

positive regulation of sequence-specific DNA binding transcription factor activity

GO:0060340

positive regulation of type I interferon-mediated signaling pathway

GO:0071360

cellular response to exogenous dsRNA

GO:0071651

positive regulation of chemokine (C-C motif) ligand 5 production

GO:0071660

positive regulation of IP-10 production