HuLPr00337

Uniprot ID

A16L2_HUMAN

Uniprot Acc

Q8NAA4;A5PL30;B2RPK5;Q658V4;Q6PID3;Q8NBG0;

Protein name

Autophagy-related protein 16-2

Comment

FUNCTION:May play a role in autophagy (By similarity).||INTERACTION:O95166:GABARAP; NbExp=1; IntAct=EBI-2946815, EBI-712001; Q9GZQ8:MAP1LC3B; NbExp=1; IntAct=EBI-2946815, EBI-373144;||SUBCELLULAR LOCATION:Cytoplasm (By similarity).||ALTERNATIVE PRODUCTS:Event=Alternative splicing; Named isoforms=3; Name=1; IsoId=Q8NAA4-1; Sequence=Displayed; Name=2; IsoId=Q8NAA4-2; Sequence=VSP 033904; Note=No experimental confirmation available; Name=3; IsoId=Q8NAA4-3; Sequence=VSP 033905; Note=No experimental confirmation available;||SIMILARITY:Belongs to the WD repeat ATG16 family.||SIMILARITY:Contains 7 WD repeats.

Subcellular localization

Cytoplasm(By similarity).

Gene name

ATG16 autophagy related 16-like 2 (S. cerevisiae)

Protein sequence

MAGPGVPGAPAARWKRHIVRQLRLRDRTQKALFLELVPAY NHLLEKAELLDKFSKKLQPEPNSVTPTTHQGPWEESELD SDQVPSLVALRVKWQEEEEGLRLVCGEMAYQVVEKGAAL GTLESELQQRQSRLAALEARVAQLREARAQQAQQVEEWR AQNAVQRAAYEALRAHVGLREAALRRLQEEARDLLERLV QRKARAAAERNLRNERRERAKQARVSQELKKAAKRTVSI SEGPDTLGDGMRERRETLALAPEPEPLEKEACEKWKRPF RSASATSLTLSHCVDVVKGLLDFKKRRGHSIGGAPEQRY QIIPVCVAARLPTRAQDVLDAHLSEVNAVRFGPNSSLLA TGGADRLIHLWNVVGSRLEANQTLEGAGGSITSVDFDPS GYQVLAATYNQAAQLWKVGEAQSKETLSGHKDKVTAAKF KLTRHQAVTGSRDRTVKEWDLGRAYCSRTINVLSYCNDV VCGDHIIISGHNDQKIRFWDSRGPHCTQVIPVQGRVTSL SLSHDQLHLLSCSRDNTLKVIDLRVSNIRQVFRADGFKC GSDWTKAVFSPDRSYALAGSCDGALYIWDVDTGKLESRL QGPHCAAVNAVAWCYSGSHMVSVDQGRKVVLWQ

Database cross reference

RefSeq Protein accession:NP_203746
RefSeq Protein gi:55743108

HLPP validation

Yes/No

Yes

Project name

French Liver;Human Liver Organelles;

GO:0005737;C:cytoplasm;IEA:UniProtKB-SubCell.

GO-F

GO:0005515;F:protein binding;IPI:IntAct.

GO-P

GO:0006914;P:autophagy;IEA:UniProtKB-KW. GO:0015031;P:protein transport;IEA:UniProtKB-KW.