Choose one of the five choices you want to search:

Gene, Transcriptome, Protein, Pathway or Disease. 

Protein basic information

LiverAtlas Protein ID

HuLPr00570

Uniprot ID

A2A2T2_HUMAN

Uniprot Acc

A2A2T2;

Protein name

Wolf-Hirschhorn syndrome candidate 1

Comment

CATALYTIC ACTIVITY:S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].||SUBCELLULAR LOCATION:Nucleus (By similarity).||SIMILARITY:Contains 1 SET domain.||SIMILARITY:Contains 1 post-SET domain.

Subcellular localization

Nucleus(By similarity).

Gene name

Wolf-Hirschhorn syndrome candidate 1

Protein sequence

MAGSFCWRMLGLVSKVGNRARCFSSMAASEEELLDFSGSE LQFNSCSLHLSLHPFFNFLLGIHSCFVCKESKTDVKRCV VTQCGKFYHEACVKKYPLTVFESRGFRCPLHSCVSCHAS NPSNPRPSKGKMMRCVRCPVAYHSGDACLAAGCSVIASN SIICTAHFTARKGKRHHAHVNVSWCFVCSKGGSLLCCES CPAAFHPDCLNIEMPDGSWFCNDCRAGKKLHFQDIIWVK LGNYRWWPAEVCHPKNVPPNIQKMKHEIGEFPVFFFGSK DYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKNALQEA EARFREIKLQREARETQESERKPPPYKHIKVNKPYGKVQ IYTADISEIPKCNCKPTDENPCGFDSECLNRMLMFECHP QVCPAGEFCQNQCFTKRQYPETKIIKTDGKGWGLVAKRD IRKGEFVNEYVGELIDEEECMARIKHAHENDITHFYMLT IDKDRIIDAGPKGNYSRFMNHSCQPNCETLKWTVNGDTR VGLFAVCDIPAGTELTFNYNLDCLGNEKTVCRCGASNCS GFLGDRPKTSTTLSSEEKGKKTKKKTRRRRAKGEGKRQS EDECFRCGDGGQLVLCDRKFCTKAYHLSCLGLGKRPFGK WECPWHHCDVCGKPSTSFCHLCPNSFCKEHQDGTAFSCT PDGRSYCCEHDLGAASVRSTKTEKPPPEPGKPKGKRRRRRGWRRVTEGK

Database cross reference

RefSeq Protein accession:NP_001035889
RefSeq Protein gi:109633019

Liver relevance

HLPP validation

Yes/No

Yes

Project name

French Liver;

Ontology annotation

GO-C

GO:0005634;C:nucleus;IEA:UniProtKB-SubCell.

GO-F

GO:0018024;F:histone-lysine N-methyltransferase activity;IEA:InterPro. GO:0008270;F:zinc ion binding;IEA:InterPro.