Protein basic information
| LiverAtlas Protein ID |
HuLPr00621 |
|
Uniprot ID |
|
|
Uniprot Acc |
A2ABF8; |
|
Protein name |
Euchromatic histone-lysine N-methyltransferase 2 |
|
Comment |
CATALYTIC ACTIVITY:S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].||CATALYTIC ACTIVITY:S-adenosyl-L-methionine + histone L-lysine = S-adenosyl-L-homocysteine + histone N(6)-methyl-L-lysine.||SUBCELLULAR LOCATION:Nucleus (By similarity).||SIMILARITY:Contains 1 SET domain.||SIMILARITY:Contains 1 post-SET domain.||SIMILARITY:Contains 1 pre-SET domain. |
|
Subcellular localization |
Nucleus(By similarity). |
|
Gene name |
|
|
Protein sequence
|
MRGLPRGRGLMRARGRGRAAPPGSRGRGRGGPHRGRGRPR SLLSLPRAQASWTPQLSTGLTSPPVPCLPSQGEAPAEMG ALLLEKETRGATERVHGSLGDTPRSEETLPKATPDSLEP AGPSSPASVTVTVGDEGADTPVGATPLIGDESENLEGDG DLRGGRILLGHATKSFPSSPSKGGSCPSRAKMSMTGAGK SPPSVQSLAMRLLSMPGAQGAAAAGSEPPPATTSPEGQP KVHRARKTMSKPGNGQPPVPEKRPPEIQHFRMSDDVHSL GKVTSDLAKRRKLNSGGGLSEELGSARRSGEVTLTKGDP GSLEEWETVVGDDFSLYYDSYSVDERVDSDSKSEVEALT EQLSEEEEEEEEEEEEEEEEEEEEEEEEDEESGNQSDRS GSSGRRKAKKKWRKDSPWVKPSRKRRKREPPRAKEPRGV SNDTSSLETERGFEELPLCSCRMEAPKIDRISERAGHKC MATESVDGELSGCNAAILKRETMRPSSRVALMVLCETHR ARMVKHHCCPGCGYFCTAGTFLECHPDFRVAHRFHKACV SQLNGMVFCPHCGEDASEAQEVTIPRGDGVTPPAGTAAP APPPLSQDVPGRADTSQPSARMRGHGEPRRPPCDPLADT IDSSGPSLTLPNGGCLSAVGLPLGPGREALEKALVIQES ERRKKLRFHPRQLYLSVKQGELQKVILMLLDNLDPNFQS DQQSKRTPLHAAAQKGSVEICHVLLQAGANINAVDKQQR TPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHA AKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKH IEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAEV LLNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGA NPELRNKEGDTAWDLTPERSDVWFALQLNRKLRLGVGNR AIRTEKIICRDVARGYENVPIPCVNGVDGEPCPEDYKYI SENCETSTMNIDRNITHLQHCTCV |
|
Database cross reference |
RefSeq Protein accession:NP_006700
|
Liver relevance
|
HLPP validation |
Yes/No |
Yes |
|
Project name |
Human Liver Organelles; |
Ontology annotation
| GO-C |
GO:0005694;C:chromosome;IEA:UniProtKB-KW. GO:0005634;C:nucleus;IEA:UniProtKB-SubCell. |
|
GO-F |
GO:0018024;F:histone-lysine N-methyltransferase activity;IEA:InterPro. GO:0008270;F:zinc ion binding;IEA:InterPro. |
Post-translational modification
| LiverAtlas Protein ID |
MOD type1 |
Position1 |
Residue1 |
Source name1 |
source ID1 |
Source method |
HLPP validation1 (Yes/no) |
Quality score |
|
HuLPr00621 |
PHOSPHORYLATION |
268 |
S |
PhosphoSitePlus |
LTP |
N |
 
|
|
|
HuLPr00621 |
PHOSPHORYLATION |
1108 |
Y |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr00621 |
PHOSPHORYLATION |
101 |
T |
PhosphoSitePlus |
HTP |
N |
|
|
|
HuLPr00621 |
PHOSPHORYLATION |
583 |
T |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr00621 |
PHOSPHORYLATION |
592 |
S |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr00621 |
PHOSPHORYLATION |
228 |
T |
PhosphoSitePlus |
HTP |
N |
|
|
|
HuLPr00621 |
TRI-METHYLATION |
242 |
K |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr00621 |
PHOSPHORYLATION |
407 |
S |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr00621 |
PHOSPHORYLATION |
97 |
S |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr00621 |
PHOSPHORYLATION |
664 |
S |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr00621 |
PHOSPHORYLATION |
41 |
S |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr00621 |
PHOSPHORYLATION |
44 |
S |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr00621 |
PHOSPHORYLATION |
578 |
T |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr00621 |
PHOSPHORYLATION |
303 |
S |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr00621 |
DI-METHYLATION |
242 |
K |
PhosphoSitePlus |
HTP |
N |
|
|
|
HuLPr00621 |
PHOSPHORYLATION |
197 |
S |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr00621 |
PHOSPHORYLATION |
230 |
S |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr00621 |
PHOSPHORYLATION |
289 |
S |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr00621 |
PHOSPHORYLATION |
1233 |
T |
PhosphoSitePlus |
LTP |
N |
|
