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Protein basic information

LiverAtlas Protein ID

HuLPr00647

Uniprot ID

A2BF25_HUMAN

Uniprot Acc

A2BF25;

Protein name

Major histocompatibility complex class I C

Comment

FUNCTION:Involved in the presentation of foreign antigens to the immune system (By similarity).||SIMILARITY:Belongs to the MHC class I family.||SIMILARITY:Contains 1 Ig-like C1-type (immunoglobulin-like) domain.

Gene name

major histocompatibility complex, class I, C

Protein sequence

MRVMAPRTLILLLSGALALTETWACSHSMRYFYTAVSRPG RGEPRFIAVGYVDDTQFVQFDSDAASPRGEPRAPWVEQE GPEYWDRETQKYKRQAQTDRVNLRKLRGYYNQSEAGSHT LQRMYGCDLGPDGRLLRGYNQFAYDGKDYIALNEDLRSW TAADKAAQITQRKWEAAREAEQRRAYLEGTCVEWLRRYL ENGKKTLQRAEHPKTHVTHHPVSDHEATLRCWALGFYPA EITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVP SGEEQRYTCHVQHEGLPEPLTLRWGPSSQPTIPIVGIVA GLAVLAVLAVLGAVMAVVMCRRKSSGHFLPTGGKGGSCS QAASSNSAQGSDESLIACKA

Database cross reference

RefSeq Protein accession:NP_002108
RefSeq Protein gi:52630342

Liver relevance

HLPP validation

Yes/No

Yes

Project name

Chinese Liver;Human Liver Organelles;

Ontology annotation

GO-C

GO:0016021;C:integral to membrane;IEA:UniProtKB-KW. GO:0042612;C:MHC class I protein complex;IEA:UniProtKB-KW.

GO-P

GO:0002474;P:antigen processing and presentation of peptide antigen via MHC class I;IEA:UniProtKB-KW. GO:0006955;P:immune response;IEA:InterPro.