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Protein basic information

LiverAtlas Protein ID

HuLPr01297

Uniprot ID

A5YM53_HUMAN

Uniprot Acc

A5YM53;

Protein name

ITGAV protein

Comment

SUBCELLULAR LOCATION:Membrane; Single-pass type I membrane protein (By similarity).||SIMILARITY:Belongs to the integrin alpha chain family.||SIMILARITY:Contains 7 FG-GAP repeats.

Subcellular localization

Membrane;Single-pass type I membrane protein(By similarity).

Gene name

integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)

Protein sequence

MAFPPRRRLRLGPRGLPLLLSGLLLPLCRAFNLDVDSPAE YSGPEGSYFGFAVDFFVPSASSRMFLLVGAPKANTTQPG IVEGGQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEF KSHQWFGASVRSKQDKILACAPLYHWRTEMKQEREPVGT CFLQDGTKTVEYAPCRSQDIDADGQGFCQGGFSIDFTKA DRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIKYN NQLATRTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVP RAARTLGMVYIYDGKNMSSLYNFTGEQMAAYFGFSVAAT DINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQRA SGDFQTTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIA APYGGEDKKGIVYIFNGRSTGLNAVPSQILEGQWAARSM PPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARP VITVNAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFC LKADGKGVLPRKLNFQVELLLDKLKQKGAIRRALFLYSR SPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPIT IFMEYRLDYRTAADTTGLQPILNQFTPANISRQAHILLD CGEDNVCKPKLEVSVDSDQKKIYIGDDNPLTLIVKAQNQ GEGAYEAELIVSIPLQADFIGVVRNNEALARLSCAFKTE NQTRQVVCDLGNPMKAGTQLLAGLRFSVHQQSEMDTSVK FDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEIRGVSSPD HIFLPIPNWEHKENPETEEDVGPVVQHIYELRNNGPSSF SKAMLHLQWPYKYNNNTLLYILHYDIDGPMNRTSDMEIN PLRIKISSLQTTEKNDTVAGQGERDHLITKRDLALSEGD IHTLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWTET FMNKENQNHSYSLKSSASFNVIEFPYKNLPIEDITNSTL VTTNVTWGIQPAPMPVPVWVIILA

Database cross reference

RefSeq Protein accession:NP_001138471
RefSeq Protein gi:223468595

Liver relevance

HLPP validation

Yes/No

Yes

Project name

Chinese Liver;Human Liver Organelles;

Ontology annotation

GO-C

GO:0008305;C:integrin complex;IEA:InterPro.

GO-F

GO:0004872;F:receptor activity;IEA:UniProtKB-KW.

GO-P

GO:0007155;P:cell adhesion;IEA:UniProtKB-KW. GO:0007229;P:integrin-mediated signaling pathway;IEA:UniProtKB-KW.