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Protein basic information

LiverAtlas Protein ID

HuLPr02115

Uniprot ID

A8K0N0_HUMAN

Uniprot Acc

A8K0N0;

Protein name

Signal recognition particle 9 kDa protein

Comment

FUNCTION:Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding (By similarity).||SUBCELLULAR LOCATION:Cytoplasm (By similarity).||SIMILARITY:Belongs to the SRP9 family.

Subcellular localization

Cytoplasm(By similarity).

Gene name

signal recognition particle 9kDa

Protein sequence

MPQYQTWEEFSRAAEKLYLADPMKARVVLKYRHSDGNLCV KVTDDLVCLVYKTDQAQDVKKIEKFHSQLMRLMVAKEAR NVTMETE

Database cross reference

RefSeq Protein accession:NP_003124
RefSeq Protein gi:4507217

Liver relevance

HLPP validation

Yes/No

Yes

Project name

French Liver;Human Liver Organelles;

Ontology annotation

GO-C

GO:0005786;C:signal recognition particle, endoplasmic reticulum targeting;IEA:UniProtKB-KW.

GO-F

GO:0008312;F:7S RNA binding;IEA:InterPro.

GO-P

GO:0045900;P:negative regulation of translational elongation;IEA:InterPro. GO:0006614;P:SRP-dependent cotranslational protein targeting to membrane;IEA:InterPro.