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Protein basic information

LiverAtlas Protein ID

HuLPr02231

Uniprot ID

A8K1U7_HUMAN

Uniprot Acc

A8K1U7;

Protein name

Cadherin 1, type 1, E-cadherin (Epithelial), isoform CRA b

Comment

FUNCTION:Cadherins are calcium dependent cell adhesion proteins (By similarity).||SUBCELLULAR LOCATION:Membrane; Single-pass type I membrane protein (By similarity).

Subcellular localization

Membrane;Single-pass type I membrane protein(By similarity).

Gene name

cadherin 1, type 1, E-cadherin (epithelial)

Protein sequence

MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFT VPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGT DGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNT VGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWV IPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQG ADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAV SSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEG ALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPD KNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQG EGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANV VITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPV NNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTS TATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSY TAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAE LDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILS DVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSP FTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYK INLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEA GLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLL PPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPE VTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADT DPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDY DYLNEWGNRFKKLADMYGGGEDD

Database cross reference

RefSeq Protein accession:NP_004351
RefSeq Protein gi:4757960

Liver relevance

HLPP validation

Yes/No

Yes

Project name

Chinese Liver;French Liver;Human Fetal Liver;Human Liver Organelles;

Ontology annotation

GO-C

GO:0016235;C:aggresome;IDA:HPA. GO:0005737;C:cytoplasm;IDA:HPA. GO:0005925;C:focal adhesion;IDA:HPA. GO:0016021;C:integral to membrane;IEA:UniProtKB-KW.

GO-P

GO:0007156;P:homophilic cell adhesion;IEA:InterPro.