Choose one of the five choices you want to search:

Gene, Transcriptome, Protein, Pathway or Disease. 

Protein basic information

LiverAtlas Protein ID

HuLPr02658

Uniprot ID

A8K5J1_HUMAN

Uniprot Acc

A8K5J1;

Protein name

Uridine monophosphate synthetase (Orotate phosphoribosyl transferase and orotidine-5'-decarboxylase), isoform CRA b

Gene name

uridine monophosphate synthetase

Protein sequence

MAVARAALGPLVTGLYDVQAFKFGDFVLKSGLSSPIYIDL RGIVSRPRLLSQVADILFQTAQNAGISFDTVCGVPYTAL PLATVICSTNQIPMLIRRKETKDYGTKRLVEGTINPGET CLIIEDVVTSGSSVLETVEVLQKEGLKVTDAIVLLDREQ GGKDKLQAHGIRLHSVCTLSKMLEILEQQKKVDAETVGR VKRFIQENVFVAANHNGSPLSIKEAPKELSFGARAELPR IHPVASKLLRLMQKKETNLCLSADVSLARELLQLADALG PSICMLKTHVDILNDFTLDVMKELITLAKCHEFLIFEDR KFADIGNTVKKQYEGGIFKIASWADLVNAHVVPGSGVVK GLQEVGLPLHRGCLLIAEMSSTGSLATGDYTRAAVRMAE EHSEFVVGFISGSRVSMKPEFLHLTPGVQLEAGGDNLGQ QYNSPQEVIGKRGSDIIIVGRGIISAADRLEAAEMYRKA AWEAYLSRLGV

Database cross reference

RefSeq Protein accession:NP_000364
RefSeq Protein gi:4507835

Liver relevance

HLPP validation

Yes/No

Yes

Project name

Chinese Liver;Human Liver Organelles;

Ontology annotation

GO-F

GO:0000287;F:magnesium ion binding;IEA:HAMAP. GO:0004588;F:orotate phosphoribosyltransferase activity;IEA:HAMAP. GO:0004590;F:orotidine-5'-phosphate decarboxylase activity;IEA:InterPro.

GO-P

GO:0006207;P:'de novo' pyrimidine base biosynthetic process;IEA:InterPro. GO:0044205;P:'de novo' UMP biosynthetic process;IEA:InterPro.

Pathway

Pathway name

Pyrimidine_Metabolism

Pathway name

UMP_Synthase_Deiciency_(Orotic_Aciduria)

Pathway name

TGF_beta_Receptor