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Protein basic information

LiverAtlas Protein ID

HuLPr03383

Uniprot ID

A8MWU7_HUMAN

Uniprot Acc

A8MWU7;C9JAR3;

Protein name

Uncharacterized protein

Comment

SUBCELLULAR LOCATION:Membrane; Multi-pass membrane protein (By similarity).||SIMILARITY:Belongs to the ligand-gated ion channel (TC 1.A.9) family.||CAUTION:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.

Subcellular localization

Membrane;Multi-pass membrane protein(By similarity).

Gene name

gamma-aminobutyric acid (GABA) A receptor, gamma 2

Protein sequence

MSSPNIWSTGSSVYSTPVFSQKMTVWILLLLSLYPGFTSQ KSDDDYEDYASNKTWVLTPKVPEGDVTVILNNLLEGYDN KLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFA QTWYDRRLKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKK ADAHWITTPNRMLRIWNDGRVLYTLRLTIDAECQLQLHN FPMDEHSCPLEFSSWSRSIAQAGMCSGVISAHYSLRFWG STDPPTLASRVAGISDGYPREEIVYQWKRSSVEVGDTRS WRLYQFSFVGLRNTTEVVKTTSGDYVVMSVYFDLSRRMG YFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGITTV LTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFSALV EYGTLHYFVSNRKPSKDKDKKKKNPLLRMFSFKAPTIDI RPRSATIQMNNATHLQERDEEYGYECLDGKDCASFFCCF EDCRTGAWRHGRIHIRIAKMDSYARIFFPTAFCLFNLVYWVSYLYL

Database cross reference

RefSeq Protein accession:NP_000807
RefSeq Protein gi:38788135

Liver relevance

HLPP validation

Yes/No

Yes

Project name

Chinese Liver;Human Liver Organelles;

Ontology annotation

GO-C

GO:0030054;C:cell junction;IEA:UniProtKB-KW. GO:0016021;C:integral to membrane;IEA:UniProtKB-KW. GO:0045211;C:postsynaptic membrane;IEA:UniProtKB-KW.

GO-F

GO:0005230;F:extracellular ligand-gated ion channel activity;IEA:InterPro. GO:0004890;F:GABA-A receptor activity;IEA:InterPro.

GO-P

GO:0006821;P:chloride transport;IEA:InterPro. GO:0007214;P:gamma-aminobutyric acid signaling pathway;IEA:InterPro.