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Protein basic information

LiverAtlas Protein ID

HuLPr03611

Uniprot ID

ABCAD_HUMAN

Uniprot Acc

Q86UQ4;Q6ZTT7;Q86WI2;Q8N248;

Protein name

ATP-binding cassette sub-family A member 13

Comment

SUBCELLULAR LOCATION:Membrane; Multi-pass membrane protein (Potential).||ALTERNATIVE PRODUCTS:Event=Alternative splicing; Named isoforms=3; Name=1; IsoId=Q86UQ4-1; Sequence=Displayed; Name=2; IsoId=Q86UQ4-2; Sequence=VSP 021069, VSP 021070; Note=No experimental confirmation available. May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay; Name=3; IsoId=Q86UQ4-3; Sequence=VSP 021068;||TISSUE SPECIFICITY:Expressed in testis, bone marrow and trachea.||SIMILARITY:Belongs to the ABC transporter superfamily.||SIMILARITY:Contains 2 ABC transporter domains.||SEQUENCE CAUTION:Sequence=BAC03623.1; Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=BAC86492.1; Type=Erroneous termination; Positions=123; Note=Translated as Glu; Sequence=BAC86492.1; Type=Frameshift; Positions=156;

Subcellular localization

Membrane;Multi-pass membrane protein(Potential).

Gene name

ATP-binding cassette, sub-family A (ABC1), member 13

Protein sequence

MGHAGCQFKALLWKNWLCRLRNPVLFLAEFFWPCILFVIL TVLRFQEPPRYRDICYLQPRDLPSCGVIPFVQSLLCNTG SRCRNFSYEGSMEHHFRLSRFQTAADPKKVNNLAFLKEI QDLAEEIHGMMDKAKNLKRLWVERSNTPDSSYGSSFFTM DLNKTEEVILKLESLHQQPHIWDFLLLLPRLHTSHDHVE DGMDVAVNLLQTILNSLISLEDLDWLPLNQTFSQVSELV LNVTISTLTFLQQHGVAVTEPVYHLSMQNIVWDPQKVQY DLKSQFGFDDLHTEQILNSSAELKEIPTDTSLEKMVCSV LSSTSEDEAEKWGHVGGCHPKWSEAKNYLVHAVSWLRVY QQVFVQWQQGSLLQKTLTGMGHSLEALRNQFEEESKPWK VVEALHTALLLLNDSLSADGPKDNHTFPKILQHLWKLQS LLQNLPQWPALKRFLQLDGALRNAIAQNLHFVQEVLICL ETSANDFKWFELNQLKLEKDVFFWELKQMLAKNAVCPNG RFSEKEVFLPPGNSSIWGGLQGLLCYCNSSETSVLNKLL GSVEDADRILQEVITWHKNMSVLIPEEYLDWQELEMQLS EASLSCTRLFLLLGADPSPENDVFSSDCKHQLVSTVIFH TLEKTQFFLEQAYYWKAFKKFIRKTCEVAQYVNMQESFQ NRLLAFPEESPCFEENMDWKMISDNYFQFLNNLLKSPTA SISRALNFTKHLLMMEKKLHTLEDEQMNFLLSFVEFFEK LLLPNLFDSSIVPSFHSLPSLTEDILNISSLWTNHLKSL KRDPSATDAQKLLEFGNEVIWKMQTLGSHWIRKEPKNLL RFIELILFEINPKLLELWAYGISKGKRAKLENFFTLLNF SVPENEILSTSFNFSQLFHSDWPKSPAMNIDFVRLSEAI ITSLHEFGFLEQEQISEALNTVYAIRNASDLFSALSEPQ KQEVDKILTHIHLNVFQDKDSALLLQIYSSFYRYIYELL NIQSRGSSLTFLTQISKHILDIIK

Database cross reference

RefSeq Protein accession:NP_689914
RefSeq Protein gi:31657092

Liver relevance

HLPP validation

Yes/No

Yes

Project name

Chinese Liver;French Liver;Human Fetal Liver;Human Liver Organelles;

Ontology annotation

GO-C

GO:0016021;C:integral to membrane;IEA:UniProtKB-KW.

GO-F

GO:0005524;F:ATP binding;IEA:UniProtKB-KW. GO:0016887;F:ATPase activity;IEA:InterPro.

GO-P

GO:0006810;P:transport;IEA:UniProtKB-KW.

Post-translational modification

LiverAtlas Protein ID

MOD type1

Position1

Residue1

Source name1

source ID1

Source method

HLPP validation1 (Yes/no)

Quality score

HuLPr03611

PHOSPHORYLATION

1773

Y

PhosphoSitePlus

980099

LTP

HTP

N