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Protein basic information

LiverAtlas Protein ID

HuLPr03646

Uniprot ID

ABHD6_HUMAN

Uniprot Acc

Q9BV23;B2R7Y9;Q6ZMF7;

Protein name

Monoacylglycerol lipase ABHD6

Comment

FUNCTION:Has 2-arachidonoylglycerol hydrolase activity (By similarity). May be a regulator of endocannabinoid signaling pathways (By similarity).||CATALYTIC ACTIVITY:Hydrolyzes glycerol monoesters of long-chain fatty acids.||SUBCELLULAR LOCATION:Membrane; Single-pass type II membrane protein (By similarity).||SIMILARITY:Belongs to the AB hydrolase superfamily.

Subcellular localization

Membrane;Single-pass type II membrane protein(By similarity).

Gene name

abhydrolase domain containing 6

Protein sequence

MDLDVVNMFVIAGGTLAIPILAFVASFLLWPSALIRIYYW YWRRTLGMQVRYVHHEDYQFCYSFRGRPGHKPSILMLHG FSAHKDMWLSVVKFLPKNLHLVCVDMPGHEGTTRSSLDD LSIDGQVKRIHQFVECLKLNKKPFHLVGTSMGGQVAGVY AAYYPSDVSSLCLVCPAGLQYSTDNQFVQRLKELQGSAA VEKIPLIPSTPEEMSEMLQLCSYVRFKVPQQILQGLVDV RIPHNNFYRKLFLEIVSEKSRYSLHQNMDKIKVPTQIIW GKQDQVLDVSGADMLAKSIANCQVELLENCGHSVVMERP RKTAKLIIDFLASVHNTDNNKKLD

Database cross reference

RefSeq Protein accession:NP_065727
RefSeq Protein gi:189027141

Liver relevance

HLPP validation

Yes/No

Yes

Project name

Chinese Liver;Human Liver Organelles;

Ontology annotation

GO-C

GO:0016021;C:integral to membrane;IEA:UniProtKB-KW.

GO-F

GO:0047372;F:acylglycerol lipase activity;IEA:EC.