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Protein basic information

LiverAtlas Protein ID

HuLPr03651

Uniprot ID

ABHEB_HUMAN

Uniprot Acc

Q96IU4;Q86VK8;Q8N8W5;

Protein name

Abhydrolase domain-containing protein 14B

Comment

FUNCTION:Has hydrolase activity towards p-nitrophenyl butyrate (in vitro). May activate transcription.||SUBUNIT:May interact with TAF1.||SUBCELLULAR LOCATION:Cytoplasm. Nucleus. Note=Predominantly cytoplasmic.||ALTERNATIVE PRODUCTS:Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q96IU4-1; Sequence=Displayed; Name=2; IsoId=Q96IU4-2; Sequence=VSP 008058; Note=No experimental confirmation available;||TISSUE SPECIFICITY:Ubiquitous. Detected in spleen, thymus, prostate, testis, ovary, small intestine, colon, peripheral blood leukocyte, heart, placenta, lung, liver, skeletal muscle, pancreas and kidney.||SIMILARITY:Belongs to the AB hydrolase superfamily. ABHD14 family.||SEQUENCE CAUTION:Sequence=AAH50650.1; Type=Erroneous initiation;

Subcellular localization

Cytoplasm.Nucleus.

Gene name

abhydrolase domain containing 14B

Protein sequence

MAASVEQREGTIQVQGQALFFREALPGSGQARFSVLLLHG IRFSSETWQNLGTLHRLAQAGYRAVAIDLPGLGHSKEAA APAPIGELAPGSFLAAVVDALELGPPVVISPSLSGMYSL PFLTAPGSQLPGFVPVAPICTDKINAANYASVKTPALIV YGDQDPMGQTSFEHLKQLPNHRVLIMKGAGHPCYLDKPE EWHTGLLDFLQGLQ

Database cross reference

RefSeq Protein accession:NP_001139786
RefSeq Protein gi:226443152

Liver relevance

HLPP validation

Yes/No

Yes

Project name

Chinese Liver;French Liver;Human Fetal Liver;Human Liver Organelles;

Ontology annotation

GO-C

GO:0005737;C:cytoplasm;IEA:UniProtKB-SubCell. GO:0005634;C:nucleus;IEA:UniProtKB-SubCell.

GO-F

GO:0016787;F:hydrolase activity;IEA:UniProtKB-KW.