Protein basic information
| LiverAtlas Protein ID |
HuLPr03660 |
|
Uniprot ID |
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|
Uniprot Acc |
Q6H8Q1;Q6H8Q0;Q6NX73;Q8N3C5;Q8N9E9;Q8N9G2;Q96JL7; |
|
Protein name |
Actin-binding LIM protein 2 |
|
Comment |
FUNCTION:May act as scaffold protein. May stimulate ABRA activity and ABRA-dependent SRF transcriptional activity.||SUBUNIT:Interacts with F-actin and ABRA.||SUBCELLULAR LOCATION:Cytoplasm. Note=In skeletal muscle, sarcomeric or cosarcomeric localization (By similarity).||ALTERNATIVE PRODUCTS:Event=Alternative splicing; Named isoforms=6; Name=1; IsoId=Q6H8Q1-1; Sequence=Displayed; Name=2; IsoId=Q6H8Q1-2; Sequence=VSP 012117; Name=3; IsoId=Q6H8Q1-3; Sequence=VSP 012113, VSP 012115, VSP 012117; Name=4; IsoId=Q6H8Q1-4; Sequence=VSP 012112, VSP 012113, VSP 012114, VSP 012116; Note=No experimental confirmation available; Name=5; IsoId=Q6H8Q1-5; Sequence=VSP 012116, VSP 012117; Note=No experimental confirmation available; Name=6; IsoId=Q6H8Q1-6; Sequence=VSP 012113, VSP 012115, VSP 012116, VSP 012118, VSP 012119; Note=No experimental confirmation available;||TISSUE SPECIFICITY:Highly expressed in skeletal muscle.||SIMILA |
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Subcellular localization |
Cytoplasm. |
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Gene name |
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Protein sequence
|
MSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQD KYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLY GTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPP GDRVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCG TEIKNGQALVALDKHWHLGCFKCKSCGKLLNAEYISKDG LPYCEADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSC ALCVRCGQMFAEGEEMYLQGSSIWHPACRQAARTEDRNK ETRTSSESIISVPASSTSGSPSRVIYAKLGGEILDYRDL AALPKSKAIYDIDRPDMISYSPYISHSAGDRQSYGEGDQ DDRSYKQCRTSSPSSTGSVSLGRYTPTSRSPQHYSRPGS ESGRSTPSLSVLSDSKPPPSTYQQAPRHFHVPDTGVKDN IYRKPPIYRQHAARRSDGEDGSLDQDNRKKSSWLMLKGD ADTRTNSPDLDTQSLSHSSGTDRDPLQRMAGDSFHSRFP YSKSDPLPGHGKNGLDQRNANLAPCGADPDASWGMREYK IYPYDSLIVTNRIRVKLPKDVDRTRLERHLSPEEFQEVF GMSIEEFDRLALWKRNDLKKKALLF |
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Database cross reference |
RefSeq Protein accession:NP_001123555
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Liver relevance
|
HLPP validation |
Yes/No |
Yes |
|
Project name |
Human Liver Organelles; |
Ontology annotation
| GO-C |
GO:0015629;C:actin cytoskeleton;IDA:MGI. GO:0005737;C:cytoplasm;NAS:UniProtKB. GO:0045111;C:intermediate filament cytoskeleton;IDA:HPA. GO:0005634;C:nucleus;IDA:HPA. |
|
GO-F |
GO:0003779;F:actin binding;IEA:InterPro. GO:0008270;F:zinc ion binding;NAS:UniProtKB. |
|
GO-P |
GO:0007411;P:axon guidance;TAS:Reactome. GO:0007010;P:cytoskeleton organization;IEA:InterPro. |
Post-translational modification
| LiverAtlas Protein ID |
MOD type1 |
Position1 |
Residue1 |
Source name1 |
source ID1 |
Source method |
HLPP validation1 (Yes/no) |
Quality score |
|
HuLPr03660 |
PHOSPHORYLATION |
332 |
S |
PhosphoSitePlus |
LTP |
N |
 
|
|
|
HuLPr03660 |
PHOSPHORYLATION |
362 |
T |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr03660 |
PHOSPHORYLATION |
363 |
S |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr03660 |
PHOSPHORYLATION |
364 |
S |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr03660 |
PHOSPHORYLATION |
366 |
S |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr03660 |
PHOSPHORYLATION |
367 |
S |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr03660 |
PHOSPHORYLATION |
368 |
T |
PhosphoSitePlus |
LTP |
N |
|
