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Protein basic information

LiverAtlas Protein ID

HuLPr03682

Uniprot ID

ACBD6_HUMAN

Uniprot Acc

Q9BR61;

Protein name

Acyl-CoA-binding domain-containing protein 6

Comment

FUNCTION:Binds long-chain acyl-coenzyme A molecules with a strong preference for unsaturated C18:1-CoA, lower affinity for unsaturated C20:4-CoA, and very weak affinity for saturated C16:0- CoA. Does not bind fatty acids.||SUBUNIT:Monomer.||SUBCELLULAR LOCATION:Cytoplasm.||TISSUE SPECIFICITY:Detected in placenta and spleen (at protein level). Detected in placenta, umbilical cord blood, CD34-positive hematopoietic progenitor cells and bone marrow.||SIMILARITY:Contains 1 ACB (acyl-CoA-binding) domain.||SIMILARITY:Contains 2 ANK repeats.

Subcellular localization

Cytoplasm.

Gene name

acyl-CoA binding domain containing 6

Protein sequence

MASSFLPAGAITGDSGGELSSGDDSGEVEFPHSPEIEETS CLAELFEKAAAHLQGLIQVASREQLLYLYARYKQVKVGN CNTPKPSFFDFEGKQKWEAWKALGDSSPSQAMQEYIAVV KKLDPGWNPQIPEKKGKEANTGFGGPVISSLYHEETIRE EDKNIFDYCRENNIDHITKAIKSKNVDVNVKDEEGRALL HWACDRGHKELVTVLLQHRADINCQDNEGQTALHYASAC EFLDIVELLLQSGADPTLRDQDGCLPEEVTGCKTVSLVL QRHTTGKA

Database cross reference

RefSeq Protein accession:NP_115736
RefSeq Protein gi:14150169

Liver relevance

HLPP validation

Yes/No

Yes

Project name

Chinese Liver;

Ontology annotation

GO-C

GO:0005737;C:cytoplasm;IDA:HPA. GO:0005634;C:nucleus;IDA:HPA.

GO-F

GO:0000062;F:fatty-acyl-CoA binding;IEA:InterPro.

Post-translational modification

LiverAtlas Protein ID

MOD type1

Position1

Residue1

Source name1

source ID1

Source method

HLPP validation1 (Yes/no)

Quality score

HuLPr03682

PHOSPHORYLATION

106

S

Phospho-ELM

42082

HTP

N

HuLPr03682

PHOSPHORYLATION

106

S

PhosphoSitePlus

3210759

LTP

N

HuLPr03682

PHOSPHORYLATION

69

Y

PhosphoSitePlus

462907

LTP

N