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Protein basic information

LiverAtlas Protein ID

HuLPr03954

Uniprot ID

AIM1_HUMAN

Uniprot Acc

Q9Y4K1;O00296;Q5VWJ2;

Protein name

Absent in melanoma 1 protein

Comment

FUNCTION:May function as suppressor of malignant melanoma. It may exert its effects through interactions with the cytoskeleton.||SIMILARITY:Belongs to the beta/gamma-crystallin family.||SIMILARITY:Contains 12 beta/gamma crystallin 'Greek key' domains.||SIMILARITY:Contains 1 ricin B-type lectin domain.

Gene name

absent in melanoma 1

Protein sequence

MEKRSSGRRSGRRRGSQKSTDSPGADAELPESAARDDAVF DDEVAPNAASDNASAEKKVKSPRAALDGGVASAASPESK PSPGTKGQLRGESDRSKQPPPASSPTKRKGRSRALEAVP APPASGPRAPAKESPPKRVPDPSPVTKGTAAESGEEAAR AIPRELPVKSSSLLPEIKPEHKRGPLPNHFNGRAEGGRS RELGRAAGAPGASDADGLKPRNHFGVGRSTVTTKVTLPA KPKHVELNLKTPKNLDSLGNEHNPFSQPVHKGNTATKIS LFENKRTNSSPRHTDIRGQRNTPASSKTFVGRAKLNLAK KAKEMEQPEKKVMPNSPQNGVLVKETAIETKVTVSEEEI LPATRGMNGDSSENQALGPQPNQDDKADVQTDAGCLSEP VASALIPVKDHKLLEKEDSEAADSKSLVLENVTDTAQDI PTTVDTKDLPPTAMPKPQHTFSDSQSPAESSPGPSLSLS APAPGDVPKDTCVQSPISSFPCTDLKVSENHKGCVLPVS RQNNEKMPLLELGGETTPPLSTERSPEAVGSECPSRVLV QVRSFVLPVESTQDVSSQVIPESSEVREVQLPTCHSNEP EVVSVASCAPPQEEVLGNEHSHCTAELAAKSGPQVIPPA SEKTLPIQAQSQGSRTPLMAESSPTNSPSSGNHLATPQR PDQTVTNGQDSPASLLNISAGSDDSVFDSSSDMEKFTEI IKQMDSAVCMPMKRKKARMPNSPAPHFAMPPIHEDHLEK VFDPKVFTFGLGKKKESQPEMSPALHLMQNLDTKSKLRP KRASAEQSVLFKSLHTNTNGNSEPLVMPEINDKENRDVT NGGIKRSRLEKSALFSSLLSSLPQDKIFSPSVTSVNTMT TAFSTSQNGSLSQSSVSQPTTEGAPPCGLNKEQSNLLPD NSLKVFNFNSSSTSHSSLKSPSHMEKYPQKEKTKEDLDS RSNLHLPETKFSELSKLKNDDMEKANHIESVIKSNLPNC ANSDTDFMGLFKSSRYDPSISFSG

Database cross reference

RefSeq Protein accession:NP_001615
RefSeq Protein gi:62988361

Liver relevance

HLPP validation

Yes/No

Yes

Project name

Human Liver Organelles;

Ontology annotation

GO-F

GO:0005529;F:sugar binding;IEA:UniProtKB-KW.

Post-translational modification

LiverAtlas Protein ID

MOD type1

Position1

Residue1

Source name1

source ID1

Source method

HLPP validation1 (Yes/no)

Quality score

HuLPr03954

PHOSPHORYLATION

971

S

Phospho-ELM

42654

HTP

N

HuLPr03954

PHOSPHORYLATION

989

S

Phospho-ELM

42655

HTP

N

HuLPr03954

ACETYLATION

747

K

PhosphoSitePlus

466039

HTP

N

HuLPr03954

PHOSPHORYLATION

329

S

PhosphoSitePlus

472257

LTP

N

HuLPr03954

PHOSPHORYLATION

525

T

PhosphoSitePlus

3913955

LTP

N

HuLPr03954

PHOSPHORYLATION

997

S

PhosphoSitePlus

14159227

LTP

N

HuLPr03954

PHOSPHORYLATION

75

S

PhosphoSitePlus

14159230

LTP

N

HuLPr03954

PHOSPHORYLATION

19

S

PhosphoSitePlus

5276091

LTP

HTP

N

HuLPr03954

PHOSPHORYLATION

20

T

PhosphoSitePlus

5276095

LTP

N

HuLPr03954

PHOSPHORYLATION

827

S

PhosphoSitePlus

7447526

LTP

N

HuLPr03954

PHOSPHORYLATION

832

S

PhosphoSitePlus

7447528

LTP

N

HuLPr03954

PHOSPHORYLATION

836

S

PhosphoSitePlus

7447530

LTP

N

HuLPr03954

PHOSPHORYLATION

837

S

PhosphoSitePlus

7447532

LTP

N

HuLPr03954

PHOSPHORYLATION

840

S

PhosphoSitePlus

7447534

LTP

N

HuLPr03954

PHOSPHORYLATION

841

S

PhosphoSitePlus

7447536

LTP

N

Pathway

Pathway name

IL4