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Protein basic information

LiverAtlas Protein ID

HuLPr04341

Uniprot ID

AQP11_HUMAN

Uniprot Acc

Q8NBQ7;

Protein name

Aquaporin-11

Comment

FUNCTION:Aquaporins facilitate the transport of water and small neutral solutes across cell membranes (By similarity).||SUBCELLULAR LOCATION:Membrane; Multi-pass membrane protein (Potential).||DOMAIN:Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).||SIMILARITY:Belongs to the MIP/aquaporin (TC 1.A.8) family. AQP11/AQP12 subfamily.

Subcellular localization

Membrane;Multi-pass membrane protein(Potential).

Gene name

aquaporin 11

Protein sequence

MSPLLGLRSELQDTCTSLGLMLSVVLLMGLARVVARQQLH RPVAHAFVLEFLATFQLCCCTHELQLLSEQHPAHPTWTL TLVYFFSLVHGLTLVGTSSNPCGVMMQMMLGGMSPETGA VRLLAQLVSALCSRYCTSALWSLGLTQYHVSERSFACKN PIRVDLLKAVITEAVCSFLFHSALLHFQEVRTKLRIHLL AALITFLVYAGGSLTGAVFNPALALSLHFMCFDEAFPQF FIVYWLAPSLGILLMILMFSFFLPWLHNNHTINKKE

Database cross reference

RefSeq Protein accession:NP_766627
RefSeq Protein gi:27370565

Liver relevance

HLPP validation

Yes/No

Yes

Project name

Chinese Liver;Human Liver Organelles;

Ontology annotation

GO-C

GO:0009986;C:cell surface;IDA:UniProtKB. GO:0016021;C:integral to membrane;IEA:UniProtKB-KW.

GO-F

GO:0005215;F:transporter activity;IEA:InterPro.