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Protein basic information

LiverAtlas Protein ID

HuLPr04495

Uniprot ID

ARSJ_HUMAN

Uniprot Acc

Q5FYB0;A2RUG0;B7ZM45;Q5FWE4;Q6UWT9;

Protein name

Arylsulfatase J

Comment

COFACTOR:Binds 1 calcium ion per subunit (By similarity).||SUBCELLULAR LOCATION:Secreted (Potential).||PTM:The conversion to 3-oxoalanine (also known as C- formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity (By similarity).||SIMILARITY:Belongs to the sulfatase family.||SEQUENCE CAUTION:Sequence=AAQ89010.1; Type=Frameshift; Positions=425;

Subcellular localization

Secreted(Potential).

Gene name

arylsulfatase family, member J

Protein sequence

MAPRGCAGHPPPPSPQACVCPGKMLAMGALAGFWILCLLT YGYLSWGQALEEEEEGALLAQAGEKLEPSTTSTSQPHLI FILADDQGFRDVGYHGSEIKTPTLDKLAAEGVKLENYYV QPICTPSRSQFITGKYQIHTGLQHSIIRPTQPNCLPLDN ATLPQKLKEVGYSTHMVGKWHLGFYRKECMPTRRGFDTF FGSLLGSGDYYTHYKCDSPGMCGYDLYENDNAAWDYDNG IYSTQMYTQRVQQILASHNPTKPIFLYIAYQAVHSPLQA PGRYFEHYRSIININRRRYAAMLSCLDEAINNVTLALKT YGFYNNSIIIYSSDNGGQPTAGGSNWPLRGSKGTYWEGG IRAVGFVHSPLLKNKGTVCKELVHITDWYPTLISLAEGQ IDEDIQLDGYDIWETISEGLRSPRVDILHNIDPIYTKAK NGSWAAGYGIWNTAIQSAIRVQHWKLLTGNPGYSDWVPP QSFSNLGPNRWHNERITLSTGKSVWLFNITADPYERVDL SNRYPGIVKKLLRRLSQFNKTAVPVRYPPKDPRSNPRLN GGVWGPWYKEETKKKKPSKNQAEKKQKKSKKKKKKQQKAVSGSTCHSGVTCG

Database cross reference

RefSeq Protein accession:NP_078866
RefSeq Protein gi:109389362

Liver relevance

HLPP validation

Yes/No

Yes

Project name

Chinese Liver;

Ontology annotation

GO-C

GO:0005576;C:extracellular region;IEA:UniProtKB-SubCell.

GO-F

GO:0004065;F:arylsulfatase activity;TAS:HGNC. GO:0046872;F:metal ion binding;IEA:UniProtKB-KW.