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Protein basic information

LiverAtlas Protein ID

HuLPr04598

Uniprot ID

AT2L1_HUMAN

Uniprot Acc

Q8TBG4;Q9H174;

Protein name

Alanine--glyoxylate aminotransferase 2-like 1

Comment

COFACTOR:Pyridoxal phosphate (Potential).||SUBUNIT:Homotetramer (By similarity).||SUBCELLULAR LOCATION:Mitochondrion (Potential).||ALTERNATIVE PRODUCTS:Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q8TBG4-1; Sequence=Displayed; Name=2; IsoId=Q8TBG4-2; Sequence=VSP 025583;||SIMILARITY:Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

Subcellular localization

Mitochondrion(Potential).

Gene name

alanine-glyoxylate aminotransferase 2-like 1

Protein sequence

MCELYSKRDTLGLRKKHIGPSCKVFFASDPIKIVRAQRQY MFDENGEQYLDCINNVAHVGHCHPGVVKAALKQMELLNT NSRFLHDNIVEYAKRLSATLPEKLSVCYFTNSGSEANDL ALRLARQFRGHQDVITLDHAYHGHLSSLIEISPYKFQKG KDVKKEFVHVAPTPDTYRGKYREDHADSASAYADEVKKI IEDAHNSGRKIAAFIAESMQSCGGQIIPPAGYFQKVAEY VHGAGGVFIADEVQVGFGRVGKHFWSFQMYGEDFVPDIV TMGKPMGNGHPVACVVTTKEIAEAFSSSGMEYFNTYGGN PVSCAVGLAVLDIIENEDLQGNAKRVGNYLTELLKKQKA KHTLIGDIRGIGLFIGIDLVKDHLKRTPATAEAQHIIYK MKEKRVLLSADGPHRNVLKIKPPMCFTEEDAKFMVDQLD RILTVLEEAMGTKTESVTSENTPCKTKMLKEAHIELLRD STTDSKENPSRKRNGMCTDTHSLLSKRLKT

Database cross reference

RefSeq Protein accession:NP_001140062
RefSeq Protein gi:226442705

Liver relevance

HLPP validation

Yes/No

Yes

Project name

Chinese Liver;Human Liver Organelles;

Ontology annotation

GO-C

GO:0005739;C:mitochondrion;IEA:UniProtKB-SubCell.

GO-F

GO:0008453;F:alanine-glyoxylate transaminase activity;NAS:UniProtKB. GO:0030170;F:pyridoxal phosphate binding;IEA:InterPro.

GO-P

GO:0006520;P:cellular amino acid metabolic process;NAS:UniProtKB.

Post-translational modification

LiverAtlas Protein ID

MOD type1

Position1

Residue1

Source name1

source ID1

Source method

HLPP validation1 (Yes/no)

Quality score

HuLPr04598

PHOSPHORYLATION

174

Y

PhosphoSitePlus

1005313

LTP

N