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Gene, Transcriptome, Protein, Pathway or Disease. 

Protein basic information

LiverAtlas Protein ID

HuLPr04937

Uniprot ID

B0YJ76_HUMAN

Uniprot Acc

B0YJ76;

Protein name

Dihydrofolate reductase

Gene name

dihydrofolate reductase

Protein sequence

MVGSLNCIVAVSQNMGIGKNGDLPWPPLRNEFRYFQRMTT TSSVEGKQNLVIMGKKTWFSIPEKNRPLKGRINLVLSRE LKEPPQGAHFLSRSLDDALKLTEQPELANKVDMVWIVGG SSVYKEAMNHPGHLKLFVTRIMQDFESDTFFPEIDLEKY KLLPEYPGVLSDVQEEKGIKYKFEVYEKND

Database cross reference

RefSeq Protein accession:NP_000782
RefSeq Protein gi:4503323

Liver relevance

HLPP validation

Yes/No

Yes

Project name

Human Liver Organelles;

Ontology annotation

GO-F

GO:0004146;F:dihydrofolate reductase activity;IEA:InterPro. GO:0050661;F:NADP binding;IEA:InterPro.

GO-P

GO:0006545;P:glycine biosynthetic process;IEA:InterPro. GO:0009165;P:nucleotide biosynthetic process;IEA:InterPro. GO:0055114;P:oxidation-reduction process;IEA:UniProtKB-KW.

Pathway

Pathway name

One_Carbon_Pool_By_Folate