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Protein basic information

LiverAtlas Protein ID

HuLPr05803

Uniprot ID

B2R8J2_HUMAN

Uniprot Acc

B2R8J2;

Protein name

Malic enzyme

Comment

SIMILARITY:Belongs to the malic enzymes family.

Gene name

malic enzyme 2, NAD(+)-dependent, mitochondrial

Protein sequence

MLSRLRVVSTTCTLACRHLHIKEKGKPLMLNPRTNKGMAF TLQERQMLGLQGLLPPKIETQDIQALRFHRNLKKMTSPL EKYIYIMGIQERNEKLFYRILQDDIESLMPIVYTPTVGL ACSQYGHIFRRPKGLFISISDRGHVRSIVDNWPENHVKA VVVTDGERILGLGDLGVYGMGIPVGKLCLYTACAGIRPD RCLPVCIDVGTDNIALLKDPFYMGLYQKRDRTQQYDDLI DEFMKAITDRYGRNTLIQFEDFGNHNAYRFLRKYREKYC TFNDDIQGTAAVALAGLLAAQKVISKPISEHKILFLGAG EAALGIANLIVMSMVENGLSEQEAQKKIWMFDKYGLLVK GRKAKIDSYQEPFTHSAPESIPDTFEDAVNILKPSTIIG VAGAGRLFTPDVIRAMASINERPVIFALSNPTAQAECTA EEAYTLTEGRCLFASGSPFGPVKLTDGRVFTPGQGNNVY IFPGVALAVILCNTRHISDSVFLEAAKALTSQLTDEELA QGRLYPPLANIQEVSINIAIKVTEYLYANKMAFRYPEPE DKAKYVKERTWRSEYDSLLPDVYEWPESASSPPVITE

Database cross reference

RefSeq Protein accession:NP_001161807
RefSeq Protein gi:270265879

Liver relevance

HLPP validation

Yes/No

Yes

Project name

Chinese Liver;Human Liver Organelles;

Ontology annotation

GO-C

GO:0005739;C:mitochondrion;IDA:HPA.

GO-F

GO:0004470;F:malic enzyme activity;IEA:InterPro. GO:0046872;F:metal ion binding;IEA:UniProtKB-KW. GO:0051287;F:NAD binding;IEA:InterPro. GO:0016616;F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;IEA:InterPro.

GO-P

GO:0006108;P:malate metabolic process;IEA:InterPro. GO:0055114;P:oxidation-reduction process;IEA:UniProtKB-KW.